UniProt Accession

 NAGA_BACSU; O34450 

Genbank Protein ID

 AF017113; AL009126 

Genbank Nucleotide ID

 AAC67285.1; CAB15506.1 

Protein Name

 N-acetylglucosamine-6-phosphate deacetylase 

Protein Synonyms/Alias

 GlcNAc 6-P deacetylase 

Gene Name

 nagA 

Gene Synonyms/Alias

 BSU35010 

Created Date

 July 27, 2013 

Organism

 Bacillus subtilis (strain 168) 

NCBI Taxa ID

 224308 

Lysine Modification

Position	Peptide	Type	References
192	FELIRHLKDESIIAS	acetylation	[1]

Reference

 [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis.
 Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG.
 Proteomics. 2013 May;13(10-11):1726-36. [PMID: 23468065] 

Functional Description

  

Sequence Annotation

 REGION 226 227 Substrate binding.
 REGION 314 316 Substrate binding.
 ACT_SITE 281 281 Proton donor/acceptor.
 METAL 63 63 Iron 1; via tele nitrogen.
 METAL 65 65 Iron 1; via tele nitrogen.
 METAL 136 136 Iron 1.
 METAL 136 136 Iron 2.
 METAL 202 202 Iron 2; via tele nitrogen.
 METAL 223 223 Iron 2; via tele nitrogen.
 METAL 281 281 Iron 1.
 BINDING 147 147 Substrate; via amide nitrogen.
 BINDING 258 258 Substrate; via tele nitrogen.  

Keyword

 3D-structure; Carbohydrate metabolism; Complete proteome; Hydrolase; Iron; Metal-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 396 AA 

Protein Sequence

Gene Ontology

 GO:0005506; F:iron ion binding; IDA:UniProtKB.
 GO:0008448; F:N-acetylglucosamine-6-phosphate deacetylase activity; IDA:UniProtKB.
 GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
 GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
 GO:0006046; P:N-acetylglucosamine catabolic process; IDA:UniProtKB.
 GO:0019262; P:N-acetylneuraminate catabolic process; IEA:UniProtKB-UniPathway. 

Interpro

 IPR006680; Amidohydro_1.
 IPR003764; GlcNAc_6-P_deAcase.
 IPR011059; Metal-dep_hydrolase_composite. 

Pfam

 PF01979; Amidohydro_1 

SMART

  

PROSITE

  

PRINTS