CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025210
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 Skiv2l 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
366IKALSNQKFRDFRNTubiquitination[1]
834MESVNGLKSLSVGRVubiquitination[1]
989PINDLQLKDVAVVEGubiquitination[1]
1002EGGLRARKLEELIRGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Helicase; Hydrolase; Nucleotide-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1244 AA 
Protein Sequence
MMETERLVLP PLDPLNLPLR ALEVGCTGRW ELLNVPGPPE STLPHGLPPC APDLCQEAEQ 60
LFLSSPAWLP LHGVEHSARK WQRKTDPWSL LAAVETPVPS DLQAQRHPTT GHILGYKEVL 120
LENTNLSATT SLSLRRPPGP ASQSLWGNPT QYPFWPGGMD EPSITDLHTR EEAEEEIDFE 180
KDLLTVPPGF KKGVDFAPKD HPAPVPGLLS LSRLLEPLDL SGGDEDEGEA AGGPRGDNAS 240
PSPSGTPLVR ASSLEDLVLK EAATVVSTPE PPKPPPQEQW AVPVDVTSPV GDFYRLIPQP 300
AFQWAFEPDV FQKQAILHLE QHDSVFVAAH TSAGKTVVAE YAIALAQKHM TRTIYTSPIK 360
ALSNQKFRDF RNTFGDVGLL TGDVQLHPEA SCLIMTTEIL RSMLYSGSDV IRDLEWVIFD 420
EVHYINDAER GVVWEEVLIM LPEHVSIILL SATVPNALEF ADWIGRLKRR QIYVISTVAR 480
PVPLEHYLFT GNSPKTQGEL FLLLDSRGAF HTQGYYAAVE AKKERMSKHA QTFGAKQPTH 540
QGGPAQDRGV YLSLLASLRT RAQLPVVVFT FSRGRCDEQA SGLTSLDLTT SSEKSEIHLF 600
LQRCLARLRG SDRQLPQVLH MSELLRRGLG VHHSGILPIL KEIVEMLFSR GLVKVLFATE 660
TFAMGVNMPA RTVVFDSMRK HDGSTFRDLL PGEYVQMAGR AGRRGLDPTG TVILLCKGRV 720
PEMADLHRMM MGKPSQLQSQ FRLTYTMILN LLRVDALRVE DMMKRSFSEF PSRKDSKAHE 780
QALADLTKRL GALEEPDVTG QLADLPEYYS WAEELTETQN MIQRRIMESV NGLKSLSVGR 840
VVVVKNEEHH NALGVILQVS SNSTSRVFTT LVLCDKPVVS DNPRDKGPAT PDVPHPDDLI 900
GFKLFLPEGP CEHTVAKLQP GDVAAISTKV LRVNGEKISE DFSKRQQQKF RKDPPLAAVT 960
TAVQELLRLA QSYPAGPPTL DPINDLQLKD VAVVEGGLRA RKLEELIRGA QCVHSPRFPA 1020
QYVKLRERMQ IQKEMERLRF LLSDQSLLLL PEYHQRVEVL RTLGYVDEAG TVKLAGRVAC 1080
AMSSHELLLT ELMFDNALSA LRPEEIAALL SGLVCQSPGD PGDQLPSTLK QGVERVKAVA 1140
KRIGEVQVAC GLNQTVEEFV GELNFGLVEV VYEWARGMPF SELAGLSGTP EGLVVRCIQR 1200
LAEMCRSLRG AARLVGEPVL GAKMETAATL LRRDIVFAAS LYTQ 1244 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 
Interpro
 IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
 IPR012961; DSH_C.
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase.
 IPR016438; RNA_helicase_ATP-dep_SK12/DOB1.
 IPR025696; rRNA_proc-arch_dom. 
Pfam
 PF00270; DEAD
 PF08148; DSHCT
 PF00271; Helicase_C
 PF13234; rRNA_proc-arch 
SMART
 SM00487; DEXDc
 SM00490; HELICc 
PROSITE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER 
PRINTS