CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033379
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Histone-lysine N-methyltransferase SETD2 
Protein Synonyms/Alias
  
Gene Name
 SETD2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
732DYSKTVVKEPVDTRVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1340 AA 
Protein Sequence
MFKGVASSRF LPKGTKTKVN LEEQGRQKVS FSFSLTKKTL QNRFLTALGN EKQSDTPNPP 60
AVPLQVDSTP KMKMEIGDTL STAEESSPPK SRVELGKIHF KKHLLHVTSR PLLATTTAVA 120
SPPTHAAPLP AVIAESTTVD SPPSSPPPPP PPAQATTLSS PAPVTEPVAL PHTPITVLMA 180
APVPLPVDVA VRSLKEPPII IVPESLEADT KQDTISNSLE EHVTQILNEQ ADISSKKEDS 240
HIGKDEEIPD SSKISLSCKK TGSKKKSSQS EGIFLGSESD EDSVRTSSSQ RSHDLKFSAS 300
IEKERDFKKS SAPLKSEDLG KPSRSKTDRD DKYFSYSKLE RDTRYVSSRC RSERERRRSR 360
SHSRSERGSR TNLSYSRSER SHYYDSDRRY HRSSPYRERT RYSRPYTDNR ARESSDSEEE 420
YKKTYSRRTS SHSSSYRDLR TSSYSKSDRD CKTETSYLEM ERRGKYSSKL ERESKRTSEN 480
EAIKRCCSPP NELGFRRGSS YSKHDSSASR YKSTLSKPIP KSDKFKNSFC CTELNEEIKQ 540
SHSFSLQTPC SKGSELRMIN KNPEREKAGS PAPSNRLNDS PTLKKLDELP IFKSEFITHD 600
SHDSIKELDS LSKVKNDQLR SFCPIELNIN GSPGAESDLA TFCTSKTDAV LMTSDDSVTG 660
SELSPLVKAC MLSSNGFQNI SRCKEKDLDD TCMLHKKSES PFRETEPLVS PHQDKLMSMP 720
VMTVDYSKTV VKEPVDTRVS CCKTKDSDIY CTLNDSNPSL CNSEAENIEP SVMKISSNSF 780
MNVHLESKPV ICDSRNLTDH SKFACEEYKQ SIGSTSSASV NHFDDLYQPI GSSGIASSLQ 840
SLPPGIKVDS LTLLKCGENT SPVLDAVLKS KKSSEFLKHA GKETIVEVGS DLPDSGKGFA 900
SRENRRNNGL SGKCLQEAQE EGNSILPERR GRPEISLDER GEGGHVHTSD DSEVVFSSCD 960
LNLTMEDSDG VTYALKCDSS GHAPEIVSTV HEDYSGSSES SNDESDSEDT DSDDSSIPRN 1020
RLQSVVVVPK NSTLPMEETS PCSSRSSQSY RHYSDHWEDE RLESRRHLYE EKFESIASKA 1080
CPQTDKFFLH KGTEKNPEIS FTQSSRKQID NRLPELSHPQ SDGVDSTSHT DVKSDPLGHP 1140
NSEETVKAKI PSRQQEELPI YSSDFEDVPN KSWQQTTFQN RPDSRLGKTE LSFSSSCEIP 1200
HVDGLHSSEE LRNLGWDFSQ EKPSTTYQQP DSSYGACGGH KYQQNAEQYG GTRDYWQGNG 1260
YWDPRSGRPP GTGVVYDRTQ GQVPDSLTDD REEEENWDQQ DGSHFSDQSD KFLLSLQKDK 1320
GSVQAPEISS NSIKDTLAVN 1340 
Gene Ontology
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0016491; F:oxidoreductase activity; IEA:InterPro.
 GO:0046914; F:transition metal ion binding; IEA:InterPro.
 GO:0001525; P:angiogenesis; IEA:Compara.
 GO:0035441; P:cell migration involved in vasculogenesis; IEA:Compara.
 GO:0060977; P:coronary vasculature morphogenesis; IEA:Compara.
 GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Compara.
 GO:0060669; P:embryonic placenta morphogenesis; IEA:Compara.
 GO:0030900; P:forebrain development; IEA:Compara.
 GO:0010452; P:histone H3-K36 methylation; IEA:Compara.
 GO:0048332; P:mesoderm morphogenesis; IEA:Compara.
 GO:0001763; P:morphogenesis of a branching structure; IEA:Compara.
 GO:0001843; P:neural tube closure; IEA:Compara.
 GO:0018023; P:peptidyl-lysine trimethylation; IEA:Compara.
 GO:0060039; P:pericardium development; IEA:Compara.
 GO:0010468; P:regulation of gene expression; IEA:Compara.
 GO:0048864; P:stem cell development; IEA:Compara. 
Interpro
 IPR009078; Ferritin-like_SF. 
Pfam
  
SMART
  
PROSITE
  
PRINTS