CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031833
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Polynucleotide kinase-3 phosphatase domain-containing protein 
Protein Synonyms/Alias
 Polynucleotide kinase-3'-phosphatase, putative 
Gene Name
 TGME49_008320, TGVEG_040070 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
321SSTSVGEKPKGQRAKacetylation[1]
649AVPSFVLKNFYRQVEacetylation[2]
Reference
 [1] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842]
 [2] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Kinase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 697 AA 
Protein Sequence
MAKTPVRSDA TGLLNQVALP SSPFWHCVDG GLWWRHYCPQ AHARFYGVQS QPASTSPGPQ 60
TASRDELQRK EPSENATGIS ALLTGYKRAR ENSAEKPGCC ASGSGEGCLF TQWSVPRLCA 120
RVNPTMESAS QDSSREDRGT EKDVFCRKNR CAGLALFDLD GTLITTKSGK KFPQGACDWK 180
LLHPPQILQK LRKLVAEGYH LVVVSNQLGV QKGHTTLMSL TEKSDALQQT LNVPLTVCLA 240
VADDFFRKPR TAAASFIFAH LLPHLHQVQC CVSSSQCCTV RCSDGGWAFD RERQLSLPPV 300
FFVGDAAGRL GVPSSTSVGE KPKGQRAKNE KAKTPKDHSA ADLKFALNVG VPFFTPEQFF 360
LEQDEVPPPL IAYFGKGTLP IGSVQSGWTR HGTHWAGVGS EVHSDQRILN STAVITEATS 420
KVKLFVPAEL VKNATPNRRM REEHFGWLRG DKVRSSSVGS TGLTGPGVKS ENGDRVTGGA 480
ENDSRGFTTD NAGNETGGDK NRHATQPQLV ILIGAPGSGK STLTETVFKD YTCIRQDDLK 540
TQAKCVKACE KALSEKRNVV IDMQNATCKT REPYIKLGKA LGTHRIRCVV LKWPEEMCKH 600
MNTYRALVGR ERAKRSRNAL STDFEGQRRP TKQPSTRFRE EAVPSFVLKN FYRQVELPSA 660
DAEGVDDVVI LDDAERHFMC EEFSDDDEMV LFGSFLD 697 
Gene Ontology
 GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
 GO:0046403; F:polynucleotide 3'-phosphatase activity; IEA:EC. 
Interpro
 IPR023214; HAD-like_dom.
 IPR006549; HAD-SF_hydro_IIIA.
 IPR027417; P-loop_NTPase.
 IPR013954; PNK3P.
 IPR015636; PNK_3Pase_euk. 
Pfam
 PF08645; PNK3P 
SMART
  
PROSITE
  
PRINTS