CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023553
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ras-related protein Rab-6A 
Protein Synonyms/Alias
 Rab-6 
Gene Name
 Rab6a 
Gene Synonyms/Alias
 Rab6 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
133NKTDLADKRQVSIEEubiquitination[1]
146EEGERKAKELNVMFIubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
 Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER) (By similarity). 
Sequence Annotation
 NP_BIND 20 28 GTP (By similarity).
 NP_BIND 68 72 GTP (By similarity).
 NP_BIND 126 129 GTP (By similarity).
 NP_BIND 156 158 GTP (By similarity).
 MOTIF 42 50 Effector region (By similarity).
 MOD_RES 2 2 N-acetylserine (By similarity).
 MOD_RES 180 180 Phosphothreonine (By similarity).
 MOD_RES 208 208 Cysteine methyl ester (By similarity).
 LIPID 206 206 S-geranylgeranyl cysteine (By
 LIPID 208 208 S-geranylgeranyl cysteine (By  
Keyword
 Acetylation; Complete proteome; ER-Golgi transport; Golgi apparatus; GTP-binding; Lipoprotein; Membrane; Methylation; Nucleotide-binding; Phosphoprotein; Prenylation; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 208 AA 
Protein Sequence
MSAGGDFGNP LRKFKLVFLG EQSVGKTSLI TRFMYDSFDN TYQATIGIDF LSKTMYLEDR 60
TVRLQLWDTA GQERFRSLIP SYIRDSTVAV VVYDITNVNS FQQTTKWIDD VRTERGSDVI 120
IMLVGNKTDL ADKRQVSIEE GERKAKELNV MFIETSAKAG YNVKQLFRRV AAALPGMEST 180
QDRSREDMID IKLEKPQEQP VNEGGCSC 208 
Gene Ontology
 GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016020; C:membrane; IDA:RGD.
 GO:0001671; F:ATPase activator activity; IDA:RGD.
 GO:0005525; F:GTP binding; ISS:UniProtKB.
 GO:0003924; F:GTPase activity; ISS:UniProtKB.
 GO:0000042; P:protein targeting to Golgi; ISS:UniProtKB.
 GO:0032482; P:Rab protein signal transduction; IC:RGD. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR003579; Small_GTPase_Rab_type. 
Pfam
 PF00071; Ras 
SMART
 SM00175; RAB 
PROSITE
 PS51419; RAB 
PRINTS
 PR00449; RASTRNSFRMNG.