CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002560
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Heterogeneous nuclear ribonucleoprotein A1 
Protein Synonyms/Alias
 hnRNP A1; PEN repeat clone P9; hnRNP core protein A1-A 
Gene Name
 Hrb98DE 
Gene Synonyms/Alias
 Pen9; CG9983 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
190KQHQLNGKMVDVKKAacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
 This protein is a component of ribonucleosomes. 
Sequence Annotation
 DOMAIN 31 107 RRM 1.
 DOMAIN 122 199 RRM 2.  
Keyword
 Alternative splicing; Complete proteome; Nucleus; Reference proteome; Repeat; Ribonucleoprotein; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 365 AA 
Protein Sequence
MVNSNQNQNG NSNGHDDDFP QDSITEPEHM RKLFIGGLDY RTTDENLKAH FEKWGNIVDV 60
VVMKDPRTKR SRGFGFITYS HSSMIDEAQK SRPHKIDGRV VEPKRAVPRQ DIDSPNAGAT 120
VKKLFVGALK DDHDEQSIRD YFQHFGNIVD INIVIDKETG KKRGFAFVEF DDYDPVDKVV 180
LQKQHQLNGK MVDVKKALPK QNDQQGGGGG RGGPGGRAGG NRGNMGGGNY GNQNGGGNWN 240
NGGNNWGNNR GGNDNWGNNS FGGGGGGGGG YGGGNNSWGN NNPWDNGNGG GNFGGGGNNW 300
NNGGNDFGGY QQNYGGGPQR GGGNFNNNRM QPYQGGGGFK AGGGNQGNYG GNNQGFNNGG 360
NNRRY 365 
Gene Ontology
 GO:0005634; C:nucleus; IDA:FlyBase.
 GO:0005703; C:polytene chromosome puff; IDA:FlyBase.
 GO:0030529; C:ribonucleoprotein complex; IDA:FlyBase.
 GO:0048027; F:mRNA 5'-UTR binding; IDA:FlyBase.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase.
 GO:0036099; P:female germ-line stem cell maintenance; IMP:FlyBase.
 GO:0033119; P:negative regulation of RNA splicing; IMP:FlyBase.
 GO:0048477; P:oogenesis; IMP:FlyBase.
 GO:0045727; P:positive regulation of translation; IMP:FlyBase.
 GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IMP:FlyBase. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
 PF00076; RRM_1 
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS