CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020571
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Acyl carrier protein, mitochondrial 
Protein Synonyms/Alias
 ACP; CI-SDAP; NADH-ubiquinone oxidoreductase 9.6 kDa subunit 
Gene Name
 Ndufab1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
88DRVLYVLKLYDKIDPacetylation[1]
92YVLKLYDKIDPEKLSacetylation[1]
97YDKIDPEKLSVNSHFacetylation[1]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123
Functional Description
 Carrier of the growing fatty acid chain in fatty acid biosynthesis in mitochondria. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity). 
Sequence Annotation
 MOD_RES 112 112 O-(pantetheine 4'-phosphoryl)serine  
Keyword
 Complete proteome; Direct protein sequencing; Electron transport; Fatty acid biosynthesis; Fatty acid metabolism; Lipid biosynthesis; Lipid metabolism; Mitochondrion; Phosphopantetheine; Reference proteome; Respiratory chain; Transit peptide; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 156 AA 
Protein Sequence
MASRVLCACV RRLPAAFAPL PRLPTLALAR PLSTTLCPEG IRRRPGALQS ALALAQVPGT 60
VTHLCRQYSD APPLTLDGIK DRVLYVLKLY DKIDPEKLSV NSHFMKDLGL DSLDQVEIIM 120
AMEDEFGFEI PDIDAEKLMC PQEIVDYIAD KKDVYE 156 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
 GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.
 GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
 GO:0009249; P:protein lipoylation; IEA:Compara. 
Interpro
 IPR003231; Acyl_carrier.
 IPR009081; Acyl_carrier_prot-like.
 IPR006162; PPantetheine_attach_site. 
Pfam
 PF00550; PP-binding 
SMART
  
PROSITE
 PS50075; ACP_DOMAIN
 PS00012; PHOSPHOPANTETHEINE 
PRINTS