UniProt Accession

 B2MG_RAT; P07151 

Genbank Protein ID

 Y00441; Y08531; X16956 

Genbank Nucleotide ID

 CAA68498.1; CAA69847.1; CAA34830.1 

Protein Name

 Beta-2-microglobulin 

Protein Synonyms/Alias

  

Gene Name

 B2m 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
108	RVKHVTLKEPKTVTW	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. 

Sequence Annotation

 DOMAIN 25 114 Ig-like C1-type.
 DISULFID 45 100  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; Disulfide bond; Immunity; Immunoglobulin domain; MHC I; Reference proteome; Secreted; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 119 AA 

Protein Sequence

Gene Ontology

 GO:0009897; C:external side of plasma membrane; IEA:Compara.
 GO:0005615; C:extracellular space; IDA:RGD.
 GO:0042612; C:MHC class I protein complex; IEA:UniProtKB-KW.
 GO:0002481; P:antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent; IEA:Compara.
 GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; IEA:UniProtKB-KW.
 GO:0006955; P:immune response; IEA:InterPro.
 GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:Compara.
 GO:0042026; P:protein refolding; IEA:Compara.
 GO:0046686; P:response to cadmium ion; IEP:RGD.
 GO:0042493; P:response to drug; IEP:RGD.
 GO:0002237; P:response to molecule of bacterial origin; IEA:Compara.
 GO:0033077; P:T cell differentiation in thymus; IEA:Compara. 

Interpro

 IPR015707; B2Microglobulin.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003006; Ig/MHC_CS.
 IPR003597; Ig_C1-set. 

Pfam

 PF07654; C1-set 

SMART

 SM00407; IGc1 

PROSITE

 PS50835; IG_LIKE
 PS00290; IG_MHC 

PRINTS