UniProt Accession

 C9J413_HUMAN; C9J413 

Genbank Protein ID

 AC078797 

Genbank Nucleotide ID

  

Protein Name

 DNA-directed RNA polymerases I, II, and III subunit RPABC3 

Protein Synonyms/Alias

  

Gene Name

 POLR2H 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
20	KDIDPEGKKFDRVSR	acetylation	[1]
20	KDIDPEGKKFDRVSR	ubiquitination	[1, 2]
21	DIDPEGKKFDRVSRL	ubiquitination	[1, 2]
118	SRVYLLMKKLAF***	ubiquitination	[2, 3]
119	RVYLLMKKLAF****	ubiquitination	[2, 3]

Reference

 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 122 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0006351; P:transcription, DNA-dependent; IEA:InterPro. 

Interpro

 IPR012340; NA-bd_OB-fold.
 IPR005570; RNA_pol_Rpb8. 

Pfam

 PF03870; RNA_pol_Rpb8 

SMART

 SM00658; RPOL8c 

PROSITE

  

PRINTS