CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006736
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Aminopeptidase Y 
Protein Synonyms/Alias
  
Gene Name
 APE3 
Gene Synonyms/Alias
 YBR286W; YBR2024 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
67PHIPYFMKPHVESEKacetylation[1]
74KPHVESEKLQDKIKVacetylation[1]
203VPPRHNEKQIALIERacetylation[1]
252GTLGEPTKHTVATVGacetylation[1]
263ATVGVPYKVGKKLIAacetylation[1]
465KNNVNNGKVLDRCYHacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 
Functional Description
  
Sequence Annotation
 CARBOHYD 85 85 N-linked (GlcNAc...) (Potential).
 CARBOHYD 96 96 N-linked (GlcNAc...) (Potential).
 CARBOHYD 115 115 N-linked (GlcNAc...) (Potential).
 CARBOHYD 150 150 N-linked (GlcNAc...) (Potential).
 CARBOHYD 162 162 N-linked (GlcNAc...) (Potential).
 CARBOHYD 371 371 N-linked (GlcNAc...) (Potential).
 CARBOHYD 427 427 N-linked (GlcNAc...) (Potential).
 CARBOHYD 480 480 N-linked (GlcNAc...) (Potential).  
Keyword
 Aminopeptidase; Complete proteome; Direct protein sequencing; Glycoprotein; Hydrolase; Metalloprotease; Protease; Reference proteome; Signal; Vacuole; Zinc; Zymogen. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 537 AA 
Protein Sequence
MHFSLKQLAV AAFYATNLGS AYVIPQFFQE AFQQEEPIEN YLPQLNDDDS SAVAANIPKP 60
HIPYFMKPHV ESEKLQDKIK VDDLNATAWD LYRLANYSTP DYGHPTRVIG SKGHNKTMEY 120
ILNVFDDMQD YYDVSLQEFE ALSGKIISFN LSDAETGKSF ANTTAFALSP PVDGFVGKLV 180
EIPNLGCEEK DYASVVPPRH NEKQIALIER GKCPFGDKSN LAGKFGFTAV VIYDNEPKSK 240
EGLHGTLGEP TKHTVATVGV PYKVGKKLIA NIALNIDYSL YFAMDSYVEF IKTQNIIADT 300
KHGDPDNIVA LGAHSDSVEE GPGINDDGSG TISLLNVAKQ LTHFKINNKV RFAWWAAEEE 360
GLLGSNFYAY NLTKEENSKI RVFMDYDMMA SPNYEYEIYD ANNKENPKGS EELKNLYVDY 420
YKAHHLNYTL VPFDGRSDYV GFINNGIPAG GIATGAEKNN VNNGKVLDRC YHQLCDDVSN 480
LSWDAFITNT KLIAHSVATY ADSFEGFPKR ETQKHKEVDI LNAQQPQFKY RADFLII 537 
Gene Ontology
 GO:0000324; C:fungal-type vacuole; IDA:SGD.
 GO:0004177; F:aminopeptidase activity; IDA:SGD.
 GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
 GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
 GO:0007039; P:vacuolar protein catabolic process; IDA:SGD. 
Interpro
 IPR007484; Peptidase_M28.
 IPR003137; Protease-assoc_domain. 
Pfam
 PF02225; PA
 PF04389; Peptidase_M28 
SMART
  
PROSITE
  
PRINTS