UniProt Accession

 UBC5_YEAST; P15732; D6VS45 

Genbank Protein ID

 X17494; Z49209; X84162; Z74355; BK006938 

Genbank Nucleotide ID

 CAA35529.1; CAA89088.1; CAA58975.1; CAA98877.1; DAA11905.1 

Protein Name

 Ubiquitin-conjugating enzyme E2-16 kDa 

Protein Synonyms/Alias

 Ubiquitin carrier protein; Ubiquitin-protein ligase 

Gene Name

 UBC5 

Gene Synonyms/Alias

 YDR059C; D4234; YD9609.13C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
91	NICLDILKDQWSPAL	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. 

Sequence Annotation

 ACT_SITE 86 86 Glycyl thioester intermediate (By
 MOD_RES 12 12 Phosphoserine (By similarity).  

Keyword

 ATP-binding; Complete proteome; Direct protein sequencing; Ligase; Nucleotide-binding; Phosphoprotein; Reference proteome; Stress response; Ubl conjugation pathway. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 148 AA 

Protein Sequence

Gene Ontology

 GO:0000502; C:proteasome complex; IPI:SGD.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.
 GO:0000209; P:protein polyubiquitination; IDA:SGD.
 GO:0006950; P:response to stress; IEA:UniProtKB-KW. 

Interpro

 IPR000608; UBQ-conjugat_E2.
 IPR023313; UBQ-conjugating_AS.
 IPR016135; UBQ-conjugating_enzyme/RWD. 

Pfam

 PF00179; UQ_con 

SMART

  

PROSITE

 PS00183; UBIQUITIN_CONJUGAT_1
 PS50127; UBIQUITIN_CONJUGAT_2 

PRINTS