CPLM-004320

CPLM 1.0 - Compendium of Protein Lysine Modification

Tag

Content

CPLM ID

CPLM-004320

UniProt Accession

INGR1_MOUSE; P15261; Q91Y85

Genbank Protein ID

M28995; M26711; M28233; M25764; J05265; AF128216; AK151079; AK153347; AK159359; AK169593; CH466562; U05960

Genbank Nucleotide ID

AAA37895.1; AAA37896.1; AAA37898.1; AAA39177.1; AAA39178.1; AAF22557.1; BAE30094.1; BAE31923.1; BAE35017.1; BAE41245.1; EDL03452.1; AAA80980.1

Protein Name

Interferon gamma receptor 1

Protein Synonyms/Alias

IFN-gamma receptor 1; IFN-gamma-R1; CD119

Gene Name

Ifngr1

Gene Synonyms/Alias

Ifngr

Created Date

July 27, 2013

Organism

Mus musculus (Mouse)

NCBI Taxa ID

10090

Lysine Modification

Position	Peptide	Type	References
292	RKSIMLPKSLLSVVK	ubiquitination	[1]
299	KSLLSVVKSATLETK	ubiquitination	[1]

Reference

[1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]

Functional Description

Receptor for interferon gamma. Two receptors bind one interferon gamma dimer.

Sequence Annotation

MOD_RES 370 370 Phosphoserine.
MOD_RES 373 373 Phosphothreonine.
CARBOHYD 61 61 N-linked (GlcNAc...) (Potential).
CARBOHYD 85 85 N-linked (GlcNAc...) (Potential).
CARBOHYD 186 186 N-linked (GlcNAc...) (Potential).
CARBOHYD 204 204 N-linked (GlcNAc...) (Potential).
CARBOHYD 211 211 N-linked (GlcNAc...) (Potential).
DISULFID 83 91 By similarity.
DISULFID 128 174 By similarity.
DISULFID 203 208 By similarity.
DISULFID 222 243 By similarity.

Keyword

Complete proteome; Disulfide bond; Glycoprotein; Immunoglobulin domain; Membrane; Phosphoprotein; Receptor; Reference proteome; Signal; Transmembrane; Transmembrane helix.

Sequence Source

UniProt (SWISSPROT/TrEMBL); GenBank; EMBL

Protein Length

477 AA

Protein Sequence

MGPQAAAGRM ILLVVLMLSA KVGSGALTST EDPEPPSVPV PTNVLIKSYN LNPVVCWEYQ 60
NMSQTPIFTV QVKVYSGSWT DSCTNISDHC CNIYEQIMYP DVSAWARVKA KVGQKESDYA 120
RSKEFLMCLK GKVGPPGLEI RRKKEEQLSV LVFHPEVVVN GESQGTMFGD GSTCYTFDYT 180
VYVEHNRSGE ILHTKHTVEK EECNETLCEL NISVSTLDSR YCISVDGISS FWQVRTEKSK 240
DVCIPPFHDD RKDSIWILVV APLTVFTVVI LVFAYWYTKK NSFKRKSIML PKSLLSVVKS 300
ATLETKPESK YSLVTPHQPA VLESETVICE EPLSTVTAPD SPEAAEQEEL SKETKALEAG 360
GSTSAMTPDS PPTPTQRRSF SLLSSNQSGP CSLTAYHSRN GSDSGLVGSG SSISDLESLP 420
NNNSETKMAE HDPPPVRKAP MASGYDKPHM LVDVLVDVGG KESLMGYRLT GEAQELS 477

Gene Ontology

GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.

Interpro

IPR003961; Fibronectin_type3.
IPR013783; Ig-like_fold.
IPR021126; Interferon_gamma_pox/mammal.
IPR008355; Interferon_gamma_rcpt_asu.

Pfam

PF07140; IFNGR1

SMART

PROSITE

PRINTS

PR01777; INTERFERONGR.