| Tag | Content |
|---|
| CPLM ID | CPLM-012908 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ubiquitin-conjugating enzyme E2 Z |
Protein Synonyms/Alias | Uba6-specific E2 conjugating enzyme 1; Use1; Ubiquitin carrier protein Z; Ubiquitin-protein ligase Z |
Gene Name | Ube2z |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 115 | RDIMSIYKEPPPGMF | acetylation | [1] | | 306 | MQDPFGEKRGHFDYQ | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Catalyzes the covalent attachment of ubiquitin to other proteins. Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation (By similarity). |
Sequence Annotation | ACT_SITE 190 190 Glycyl thioester intermediate (By
MOD_RES 339 339 Phosphoserine (By similarity). |
Keyword | Apoptosis; ATP-binding; Complete proteome; Cytoplasm; Ligase; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Ubl conjugation pathway. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 356 AA |
Protein Sequence | MAESPTEEAA TATAGAGAAG PGASGVAGVV GVSGSGGGFG PPFLPDVWAA AAAAGGAGGP 60
GSGLAPLPGL PPSAAAHGAA LLSHWDPTLS SDWDGERTAP QCLLRIKRDI MSIYKEPPPG 120
MFVVPDTVDM TKIHALITGP FDTPYEGGFF LFVFRCPPDY PIHPPRVKLM TTGNNTVRFN 180
PNFYRNGKVC LSILGTWTGP AWSPAQSISS VLISIQSLMT ENPYHNEPGF EQERHPGDSK 240
NYNECIRHET IRVAVCDMME GKCPCPEPLR GVMEKSFLEY YDFYEVACKD RLHLQGQTMQ 300
DPFGEKRGHF DYQSLLMRLG LIRQKVLERL HNENAEMDSD SSSSGTETDL HGSLRV 356 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |