CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011428
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Myosin light chain 2 
Protein Synonyms/Alias
 Calmodulin-like myosin light chain MLC2; MYO1 light chain 2; Myosin-1 light chain 
Gene Name
 MLC2 
Gene Synonyms/Alias
 YPR188C; P9677.10 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
155EERTFRGKLFLDSITubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Regulatory light chain for the class II conventional myosin MYO1. May play a role in the disassembly of the MYO1 ring at the bud neck at the end of its contraction during cytokinesis. 
Sequence Annotation
 DOMAIN 15 50 EF-hand 1.
 DOMAIN 92 127 EF-hand 2.  
Keyword
 Calcium; Cell cycle; Cell division; Complete proteome; Metal-binding; Motor protein; Myosin; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 163 AA 
Protein Sequence
MDHSESLTFN QLTQDYINKL KDAFQMLDED EDGLISRGDL TKIYATLGKT LTDEEWSKMV 60
PDNDTSTAEV GEEGVSFPIF LSIMGKNLSQ FPEREELEES LKAIGRGHDL NVPLNEVIDS 120
LKEAGFENPE EEFAKLFKLF TTNQQATEER TFRGKLFLDS ITD 163 
Gene Ontology
 GO:0000142; C:cellular bud neck contractile ring; IDA:SGD.
 GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0000916; P:actomyosin contractile ring contraction; IMP:SGD. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom. 
Pfam
  
SMART
  
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 
PRINTS