| Tag | Content |
|---|
| CPLM ID | CPLM-002756 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Tubulin alpha-1 chain |
Protein Synonyms/Alias | |
Gene Name | TUBA1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Chlamydomonas reinhardtii (Chlamydomonas smithii) |
NCBI Taxa ID | 3055 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 40 | DGQMPSDKTIGGGDD | acetylation | [1] |
|
Reference | [1] Identification of an acetylation site of Chlamydomonas alpha-tubulin. LeDizet M, Piperno G. Proc Natl Acad Sci U S A. 1987 Aug;84(16):5720-4. [ PMID: 2441392] |
Functional Description | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. |
Sequence Annotation | NP_BIND 142 148 GTP (Potential).
MOD_RES 40 40 N6-acetyllysine. |
Keyword | Acetylation; Cytoplasm; Cytoskeleton; GTP-binding; Microtubule; Nucleotide-binding. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 451 AA |
Protein Sequence | MREVISIHIG QAGIQVGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDAFN TFFSETGAGK 60
HVPRCIFLDL EPTVVDEVRT GTYRQLFHPE QLISGKEDAA NNFARGHYTI GKEIVDLALD 120
RIRKLADNCT GLQGFLVFNA VGGGTGSGLG SLLLERLSVD YGKKSKLGFT VYPSPQVSTA 180
VVEPYNSVLS THSLLEHTDV AVMLDNEAIY DICRRSLDIE RPTYTNLNRL IAQVISSLTA 240
SLRFDGALNV DITEFQTNLV PYPRIHFMLS SYAPIISAEK AYHEQLSVAE ITNAAFEPAS 300
MMVKCDPRHG KYMACCLMYR GDVVPKDVNA SVATIKTKRT IQFVDWCPTG FKCGINYQPP 360
TVVPGGDLAK VQRAVCMISN STAIGEIFSR LDHKFDLMYA KRAFVHWYVG EGMEEGEFSE 420
AREDLAALEK DFEEVGAESA EGAGEGEGEE Y 451 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW. GO:0005874; C:microtubule; IEA:UniProtKB-KW. GO:0005525; F:GTP binding; IEA:UniProtKB-KW. GO:0003924; F:GTPase activity; IEA:InterPro. GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro. GO:0007017; P:microtubule-based process; IEA:InterPro. GO:0051258; P:protein polymerization; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |