CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034224
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 COP9 signalosome complex subunit 6 
Protein Synonyms/Alias
  
Gene Name
 Cops6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
72EEKIIIDKEYYYTKEacetylation[1]
72EEKIIIDKEYYYTKEubiquitination[2]
78DKEYYYTKEEQFKQVacetylation[1]
213KLILEYVKASEAGEVubiquitination[2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 297 AA 
Protein Sequence
MASGVTGSVS VALHPLVILN ISDHWIRMRS QEGRPMQVIG ALIGKQEGRN IEVMNSFELL 60
SHTVEEKIII DKEYYYTKEE QFKQVFKELE FLGWYTTGGP PDPSDIHVHK QVCEIIESPL 120
FLKLNPMTKH TDLPVSVFES VIDIINGEAT MLFAELTYTL ATEEAERIGV DHVARMTATG 180
SGENSTVAEH LIAQHSAIKM LHSRVKLILE YVKASEAGEV PFNHEILREA YALCHCLPVL 240
STDKFKTDFY DQCNDVGLMA YLGTITKTCN TMNQFVNKFN VLYDRQGIGR RMRGLFF 297 
Gene Ontology
 GO:0008180; C:signalosome; IDA:MGI.
 GO:0010388; P:cullin deneddylation; IEA:Compara. 
Interpro
 IPR000555; JAB1_Mov34_MPN_PAD1.
 IPR024969; Rpn11/EIF3F_C. 
Pfam
 PF01398; JAB
 PF13012; MitMem_reg 
SMART
 SM00232; JAB_MPN 
PROSITE
  
PRINTS