Tag | Content |
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CPLM ID | CPLM-002746 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Signal recognition particle 19 kDa protein |
Protein Synonyms/Alias | SRP19 |
Gene Name | SRP19 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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102 | LVQFPSRKSVMLYAA | ubiquitination | [1] | 121 | KLKTRTQKTGGADQS | ubiquitination | [1] |
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Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Signal-recognition-particle assembly, binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. |
Sequence Annotation | REGION 136 144 Basic region, potentially involved in MOD_RES 2 2 N-acetylalanine. |
Keyword | 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Polymorphism; Reference proteome; Ribonucleoprotein; RNA-binding; Signal recognition particle. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 144 AA |
Protein Sequence | MACAAARSPA DQDRFICIYP AYLNNKKTIA EGRRIPISKA VENPTATEIQ DVCSAVGLNV 60 FLEKNKMYSR EWNRDVQYRG RVRVQLKQED GSLCLVQFPS RKSVMLYAAE MIPKLKTRTQ 120 KTGGADQSLQ QGEGSKKGKG KKKK 144 |
Gene Ontology | GO:0005829; C:cytosol; TAS:Reactome. GO:0005739; C:mitochondrion; IDA:HPA. GO:0005730; C:nucleolus; IDA:MGI. GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IDA:UniProtKB. GO:0008312; F:7S RNA binding; IDA:UniProtKB. GO:0042493; P:response to drug; IDA:UniProtKB. GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome. GO:0006412; P:translation; TAS:Reactome. |
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