CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041052
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Bcl-2-associated transcription factor 1 
Protein Synonyms/Alias
  
Gene Name
 Bclaf1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
330EGDQETAKTGKFLKRacetylation[1]
419SVLADQGKSFATSSHacetylation[1, 2, 3]
435NTEEEGPKYKSKVSLacetylation[1, 2]
473VERPSTAKDKHKEEDacetylation[1]
679GFKEEIQKGDKKLRCacetylation[1]
735YKEYKPYKDDSKHKGacetylation[1]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 870 AA 
Protein Sequence
MGRSNSRSHS SRSKSRSQSS SRSRSRSHSR KKRYSSRSRS RTYSRSRSRD RIYSRDYRRD 60
YRNNRGMRRP YGYRGRGRGY YQGGGGRYHR GGYRPVWNRR HSRSPRRGRS RSRSPKRRSV 120
SSQRSRSRSR RSYRSSRSPR SSSSRSSSPY SKSPVSKRRG SQEKQTKKAE GEPQEESPLK 180
SKSQEEPKDT FEHDPSESID EFNKSATSGD IWPGLSAYDN SPRSPHSPSP IATPPSQSSS 240
CSDAPMLSTV HSAKNTPSQH SHSIQHSPER SGSGSVGNGS SRYSPSQNSP IHHIPSRRSP 300
AKTITPQNAP REESRGRSSF YPEGDQETAK TGKFLKRFTD EESRVFLLDR GNIRDKEAPK 360
EKGSEKGRAD GDWDDQEVLD YFSDKESAKQ KFHDSEGDDT EETEDYRQFR KSVLADQGKS 420
FATSSHRNTE EEGPKYKSKV SLKGNRESDG FREEKNYKLK ETAYIVERPS TAKDKHKEED 480
KGSDRITVKK EVQSPEQVKS EKLKELFDYS PPLHKSLDAR EKSIFREESP LRIKMIASDS 540
HRPEVKLKMA PVPLDDSNRP ASLTKDRLLA STLVHSVKKE QEFRSIFDHI KLPQANKSTS 600
ESFIQHIVSL VHHVKEQYFK SPAVTLNERF TSYQKATEEH STRQKSPEIH RRIDISPSAL 660
RKHTRLAGEE RGFKEEIQKG DKKLRCDSAD LRHDIDRRRK ERSKERGDSK GSRESSGSRK 720
QEKTPKDYKE YKPYKDDSKH KGRERDHSRS SSSSASPSSP SSREEKESKK EREEEFKTHH 780
EMKDYSGFAG VSRPRGTFHD DRDDGVDYWA KRGRGRGTFQ RGRGRFNFKK SGSSPKWTHD 840
KYQGDGIVED DEETMENNEE KKDRRKEEKE 870 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0006917; P:induction of apoptosis; IEA:InterPro.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:InterPro.
 GO:2001022; P:positive regulation of response to DNA damage stimulus; IEA:InterPro. 
Interpro
 IPR026668; Bcl-2_assoc_TF1. 
Pfam
  
SMART
  
PROSITE
  
PRINTS