CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033949
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Long-chain-fatty-acid--CoA ligase 1 
Protein Synonyms/Alias
  
Gene Name
 Acsl1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
52ATRPKALKPPCDLSMacetylation[1, 2]
52ATRPKALKPPCDLSMubiquitination[3]
Reference
 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 86 AA 
Protein Sequence
MEVHELFRYF RMPELIDIRQ YVRTLPTNTL MGFGAFAALT TFWYATRPKA LKPPCDLSMQ 60
SVEIAGTTDG IRRSAVLEDD KLLVYY 86 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:Compara.
 GO:0005741; C:mitochondrial outer membrane; IEA:Compara.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005778; C:peroxisomal membrane; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0004467; F:long-chain fatty acid-CoA ligase activity; IEA:Compara.
 GO:0033211; P:adiponectin-mediated signaling pathway; IMP:MGI.
 GO:0008610; P:lipid biosynthetic process; IEA:Compara.
 GO:0044539; P:long-chain fatty acid import; IEA:Compara.
 GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IMP:MGI.
 GO:0042493; P:response to drug; IEA:Compara.
 GO:0007584; P:response to nutrient; IEA:Compara.
 GO:0034201; P:response to oleic acid; IEA:Compara.
 GO:0014070; P:response to organic cyclic compound; IEA:Compara.
 GO:0006641; P:triglyceride metabolic process; IEA:Compara.
 GO:0042178; P:xenobiotic catabolic process; IEA:Compara. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS