CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000810
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized ABC transporter ATP-binding protein Rv2477c/MT2552 
Protein Synonyms/Alias
  
Gene Name
 Rv2477c, MT2552 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mycobacterium tuberculosis 
NCBI Taxa ID
 1773 
Lysine Modification
Position
Peptide
Type
References
338YDGRALIKDLSFSLPpupylation[1]
Reference
 [1] Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] .
 Festa RA, McAllister F, Pearce MJ, Mintseris J, Burns KE, Gygi SP, Darwin KH.
 PLoS One. 2010 Jan 6;5(1):e8589. [PMID: 20066036] 
Functional Description
 Probably part of an ABC transporter complex. Probably responsible for energy coupling to the transport system (By similarity). 
Sequence Annotation
 DOMAIN 6 256 ABC transporter 1.
 DOMAIN 322 539 ABC transporter 2.
 NP_BIND 38 45 ATP (Potential).
 NP_BIND 354 361 ATP (Potential).
 CROSSLNK 338 338 Isoglutamyl lysine isopeptide (Lys-Gln)  
Keyword
 ATP-binding; Complete proteome; Isopeptide bond; Nucleotide-binding; Reference proteome; Repeat; Transport; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 558 AA 
Protein Sequence
MAEFIYTMKK VRKAHGDKVI LDDVTLSFYP GAKIGVVGPN GAGKSSVLRI MAGLDKPNNG 60
DAFLATGATV GILQQEPPLN EDKTVRGNVE EGMGDIKIKL DRFNEVAELM ATDYTDELME 120
EMGRLQEELD HADAWDLDAQ LEQAMDALRC PPADEPVTNL SGGERRRVAL CKLLLSKPDL 180
LLLDEPTNHL DAESVQWLEQ HLASYPGAIL AVTHDRYFLD NVAEWILELD RGRAYPYEGN 240
YSTYLEKKAE RLAVQGRKDA KLQKRLTEEL AWVRSGAKAR QAKSKARLQR YEEMAAEAEK 300
TRKLDFEEIQ IPVGPRLGNV VVEVDHLDKG YDGRALIKDL SFSLPRNGIV GVIGPNGVGK 360
TTLFKTIVGL ETPDSGSVKV GETVKLSYVD QARAGIDPRK TVWEVVSDGL DYIQVGQTEV 420
PSRAYVSAFG FKGPDQQKPA GVLSGGERNR LNLALTLKQG GNLILLDEPT NDLDVETLGS 480
LENALLNFPG CAVVISHDRW FLDRTCTHIL AWEGDDDNEA KWFWFEGNFG AYEENKVERL 540
GVDAARPHRV THRKLTRG 558 
Gene Ontology
 GO:0005618; C:cell wall; IDA:MTBBASE.
 GO:0005829; C:cytosol; IDA:MTBBASE.
 GO:0005886; C:plasma membrane; IDA:MTBBASE.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC.
 GO:0040007; P:growth; IMP:MTBBASE.
 GO:0006810; P:transport; IEA:UniProtKB-KW. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR022374; ABC_ATP-bd_ChvD.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS