UniProt Accession

 RRBP1_HUMAN; Q9P2E9; A2A2S6; A6NCN6; O75300; O75301; Q5W165; Q96SB2; Q9BWP1; Q9H476 

Genbank Protein ID

 AF006751; AF007575; AB037819; AL132765; AL132765; AL833822; BC000099 

Genbank Nucleotide ID

 AAC25977.1; AAC25978.1; BAA92636.2; CAC10587.1; CAH74034.1; CAD38684.1; AAH00099.4 

Protein Name

 Ribosome-binding protein 1 

Protein Synonyms/Alias

 180 kDa ribosome receptor homolog; RRp; ES/130-related protein; Ribosome receptor protein 

Gene Name

 RRBP1 

Gene Synonyms/Alias

 KIAA1398 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
131	VPAMPQEKLASSPKD	ubiquitination	[1]
588	EGSPNQGKKADAAAN	ubiquitination	[2]
589	GSPNQGKKADAAANQ	ubiquitination	[2]
598	DAAANQGKKTESASV	ubiquitination	[2]
1262	RQQLSEMKSHVEDGD	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

 Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane (By similarity). 

Sequence Annotation

 REPEAT 197 206 1.
 REPEAT 207 216 2.
 REPEAT 217 226 3.
 REPEAT 227 236 4.
 REPEAT 237 246 5.
 REPEAT 247 256 6.
 REPEAT 257 266 7.
 REPEAT 267 276 8.
 REPEAT 277 286 9.
 REPEAT 287 296 10.
 REPEAT 297 306 11.
 REPEAT 307 316 12.
 REPEAT 317 326 13.
 REPEAT 327 336 14.
 REPEAT 337 346 15.
 REPEAT 347 356 16.
 REPEAT 357 366 17.
 REPEAT 367 376 18.
 REPEAT 377 386 19.
 REPEAT 387 396 20.
 REPEAT 397 406 21.
 REPEAT 407 416 22.
 REPEAT 417 426 23.
 REPEAT 427 436 24.
 REPEAT 437 446 25.
 REPEAT 447 456 26.
 REPEAT 457 466 27.
 REPEAT 467 476 28.
 REPEAT 477 486 29.
 REPEAT 487 496 30.
 REPEAT 497 506 31.
 REPEAT 507 516 32.
 REPEAT 517 526 33.
 REPEAT 527 534 34; approximate.
 REPEAT 535 544 35.
 REPEAT 545 554 36; approximate.
 REPEAT 555 564 37.
 REPEAT 565 574 38.
 REPEAT 575 584 39; approximate.
 REPEAT 585 594 40.
 REPEAT 595 604 41.
 REGION 197 604 41 X 10 AA approximate tandem repeats of
 MOD_RES 225 225 Phosphothreonine.
 MOD_RES 235 235 Phosphothreonine.
 MOD_RES 245 245 Phosphothreonine.
 MOD_RES 255 255 Phosphothreonine.
 MOD_RES 533 533 Phosphoserine.
 MOD_RES 583 583 Phosphoserine.
 MOD_RES 615 615 Phosphoserine.
 MOD_RES 978 978 Phosphoserine.
 MOD_RES 1276 1276 Phosphoserine.
 MOD_RES 1277 1277 Phosphoserine.  

Keyword

 Alternative splicing; Complete proteome; Endoplasmic reticulum; Membrane; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Repeat; Translocation; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 1410 AA 

Protein Sequence

Gene Ontology

 GO:0030176; C:integral to endoplasmic reticulum membrane; NAS:UniProtKB.
 GO:0005840; C:ribosome; TAS:ProtInc.
 GO:0004872; F:receptor activity; TAS:ProtInc.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0007165; P:signal transduction; NAS:UniProtKB.
 GO:0006412; P:translation; TAS:ProtInc. 

Interpro

 IPR007794; Rib_rcpt_KP. 

Pfam

 PF05104; Rib_recp_KP_reg 

SMART

  

PROSITE

  

PRINTS