| Tag | Content |
|---|
| CPLM ID | CPLM-007725 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Elongation factor Ts, mitochondrial |
Protein Synonyms/Alias | EF-Ts; EF-TsMt |
Gene Name | TSFM |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 213 | QLALAIGKLGENMIL | ubiquitination | [1] |
|
Reference | [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties. Chen Z, Zhou Y, Song J, Zhang Z. Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [ PMID: 23603789] |
Functional Description | Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity). |
Sequence Annotation | MOD_RES 324 324 Phosphothreonine. |
Keyword | 3D-structure; Alternative splicing; Cardiomyopathy; Complete proteome; Disease mutation; Elongation factor; Mitochondrion; Phosphoprotein; Protein biosynthesis; Reference proteome; Transit peptide. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 325 AA |
Protein Sequence | MSLLRSLRVF LVARTGSYPA GSLLRQSPQP RHTFYAGPRL SASASSKELL MKLRRKTGYS 60
FVNCKKALET CGGDLKQAEI WLHKEAQKEG WSKAAKLQGR KTKEGLIGLL QEGNTTVLVE 120
VNCETDFVSR NLKFQLLVQQ VALGTMMHCQ TLKDQPSAYS KVQWLTPVNL ALWEAEAGGS 180
LEGFLNSSEL SGLPAGPDRE GSLKDQLALA IGKLGENMIL KRAAWVKVPS GFYVGSYVHG 240
AMQSPSLHKL VLGKYGALVI CETSEQKTNL EDVGRRLGQH VVGMAPLSVG SLDDEPGGEA 300
ETKMLSQPYL LDPSITLGQY VQPQGVSVVD FVRFECGEGE EAAETE 346 |
Gene Ontology | GO:0005739; C:mitochondrion; IDA:HPA. GO:0005634; C:nucleus; IDA:HPA. GO:0003746; F:translation elongation factor activity; IEA:HAMAP. GO:0032784; P:regulation of DNA-dependent transcription, elongation; TAS:ProtInc. GO:0006414; P:translational elongation; TAS:ProtInc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |