CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029077
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Tetraspanin-14 
Protein Synonyms/Alias
  
Gene Name
 TSPAN14 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
149GASYSREKCGVPFSCubiquitination[1]
181VRIQLKSKWDESIFTubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 223 AA 
Protein Sequence
MERKVLPCFL CLFQGVLSDL TKVTRMHGID PVVLVLMVGV VMFTLGFAGC VGALRENICL 60
LNFFCGTIVL IFFLELAVAV LAFLFQDWVR DRFREFFESN IKSYRDDIDL QNLIDSLQKA 120
NQCCGAYGPE DWDLNVYFNC SGASYSREKC GVPFSCCVPD PAQKVVNTQC GYDVRIQLKS 180
KWDESIFTKG CIQALESWLP RNIYIVAGVF IAISLLQIFG IFL 223 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR000301; Tetraspanin.
 IPR018499; Tetraspanin/Peripherin.
 IPR018503; Tetraspanin_CS.
 IPR008952; Tetraspanin_EC2. 
Pfam
 PF00335; Tetraspannin 
SMART
  
PROSITE
 PS00421; TM4_1 
PRINTS
 PR00259; TMFOUR.