UniProt Accession

 LMA2L_HUMAN; Q9H0V9; D3DXH6; Q53GV3; Q53S67; Q63HN6; Q8NBQ6; Q9BQ14 

Genbank Protein ID

 AJ549957; AL136617; AY358929; AK222828; AK075347; BX648002; AC068539; CH471207; CH471207; BC000347; BC005822; BC005862; BC067265 

Genbank Nucleotide ID

 CAD71268.1; CAB66552.1; AAQ89288.1; BAD96548.1; BAC11559.1; CAH56196.1; AAX93211.1; EAW71341.1; EAW71343.1; AAH00347.2; AAH05822.2; AAH05862.2; AAH67265.1 

Protein Name

 VIP36-like protein 

Protein Synonyms/Alias

 Lectin mannose-binding 2-like; LMAN2-like protein 

Gene Name

 LMAN2L 

Gene Synonyms/Alias

 VIPL; PSEC0028; UNQ368/PRO704 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
94	LTPDMQSKQGALWNR	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53. 

Sequence Annotation

 DOMAIN 49 274 L-type lectin-like.
 REGION 161 163 Carbohydrate binding (By similarity).
 REGION 258 260 Carbohydrate binding (By similarity).
 MOTIF 344 346 Endoplasmic reticulum retention signal.
 METAL 159 159 Calcium (By similarity).
 METAL 161 161 Calcium (By similarity).
 METAL 163 163 Calcium (By similarity).
 METAL 191 191 Calcium (By similarity).
 BINDING 93 93 Carbohydrate (By similarity).
 BINDING 128 128 Carbohydrate (By similarity).
 BINDING 188 188 Carbohydrate (By similarity).
 CARBOHYD 181 181 N-linked (GlcNAc...) (high mannose).
 DISULFID 200 237 By similarity.  

Keyword

 Alternative splicing; Complete proteome; Disulfide bond; Endoplasmic reticulum; Glycoprotein; Golgi apparatus; Lectin; Membrane; Metal-binding; Reference proteome; Signal; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 348 AA 

Protein Sequence

Gene Ontology

 GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.
 GO:0030134; C:ER to Golgi transport vesicle; NAS:UniProtKB.
 GO:0005794; C:Golgi apparatus; IDA:UniProtKB.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; TAS:UniProtKB.
 GO:0005537; F:mannose binding; TAS:UniProtKB.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:UniProtKB.
 GO:0006457; P:protein folding; NAS:UniProtKB.
 GO:0015031; P:protein transport; IMP:UniProtKB. 

Interpro

 IPR008985; ConA-like_lec_gl_sf.
 IPR013320; ConA-like_subgrp.
 IPR005052; Lectin_leg. 

Pfam

 PF03388; Lectin_leg-like 

SMART

  

PROSITE

 PS51328; L_LECTIN_LIKE 

PRINTS