CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028367
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CG11198, isoform A 
Protein Synonyms/Alias
  
Gene Name
 ACC 
Gene Synonyms/Alias
 CG11198; Dmel_CG11198 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
2266YKEKDLVKTIHRLDPacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 Biotin; Complete proteome; Ligase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2482 AA 
Protein Sequence
MLITILGTLA AFLAFLLTLI FGRGQKRSKP VQSSAATSAT TATTGDSDNG NTNHNSSVIA 60
ATATATTTSS KPPIAPAAPP SAVKASDKRF PKACIKKVQF SSESLRSDVD ELCDQLKDSA 120
LSNLSNDNIR IACHQNNNNS SINKNQNNNS IDISISISKM SETNESNDTA AQSAEGERPS 180
FLVGDEIDER AAEAGEACDE FPLKMQNDVR QNGDISERRK RLRPSMSRGT GLGQDRHQDR 240
DFHIATTEEF VKRFGGTRVI NKVLIANNGI AAVKCMRSIR RWAYEMFKNE RAIRFVVMVT 300
PEDLKANAEY IKMADHYVPV PGGSNNNNYA NVELIVDIAL RTQVQAVWAG WGHASENPKL 360
PELLHKEGLV FLGPPERAMW ALGDKVASSI VAQTAEIPTL PWSGSDLKAQ YSGKKIKISS 420
ELFARGCVTN VEQGLAAVNK IGFPVMIKAS EGGGGKGIRR VDTTEEFPGL FRQVQAEVPG 480
SPIFVMKLAR GARHLEVQLL ADQYGNAISL FGRDCSIQRR HQKIIEEAPA IVAQPEVFED 540
MEKAAVRLAK MVGYVSAGTV EYLYDPEGRY FFLELNPRLQ VEHPCTEMVA DVNLPAAQLQ 600
IGMGIPLYRL KDIRLLYGES PWGSSVIDFE NPPNKPRPSG HVIAARITSE NPDEGFKPSS 660
GTVQELNFRS SKNVWGYFSV AASGGLHEFA DSQFGHCFSW GENRQQAREN LVIALKELSI 720
RGDFRTTVEY LITLLETNRF LDNSIDTAWL DALIAERVQS EKPDILLGVM CGSLHIADRQ 780
ITESFSSFQT SLEKGQIQAA NTLTNVVDVE LINDGIRYKV QAAKSGANSY FLLMNSSFKE 840
IEVHRLSDGG LLISLEGASY TTYMKEEVDR YRIVIGNQTC VFEKENDPSL LRSPSAGKLI 900
NMIVEDGAHV SKGQAYAEIE VMKMVMTLTS QEAGTVTFVR RPGAVLDAGS LLGHLELDDP 960
SLVTKAQPFK GQFLQPENAP VPEKLNRVHN TYKSILENTL AGYCLPEPFN AQRLRDIIEK 1020
FMQSLRDPSL PLLELQEVIA SISGRIPISV EKKIRKLMTL YERNITSVLA QFPSQQIASV 1080
IDSHAATLQK RADRDVFFLT TQSIVQLVQR YRNGIRGRMK AAVHELLRQY YDVESQFQYG 1140
HYDKCVGLVR EHNKDDMQTV VNTIFSHSQV AKKNLLVTLL IDHLWANEPG LTDELANTLS 1200
ELTSLNRAEH SRVALRSRQV LIAAHQPAYE LRHNQMESIF LSAVDMYGHD FHPENLQRLI 1260
LSETSIFDIL HDFFYHSNRA VCNAALEVYV RRAYTSYELT CLQHLELSGG LPLVHFQFLL 1320
PTAHPNRLFS RMSSPDGLDQ AAAESLGNSF VRTGAIAAFD SFEHFEMYSD EILDLLEDFV 1380
SPAMVNAKVL EAVEAADSIS DSRHSTSINV SLSDPVTRAN AAEEAKSTEP IHIVSVAVRE 1440
TGELDDLQMA QIFGNYCQEH NEELFQRRIR RITFAALKKR QFPKFFTFRA RDKFTEDRIY 1500
RHLEPASAFH LELNRMKTYD LEALPTANQK MHLYLGKAKV SKGQEVTDYR FFIRSIIRHS 1560
DLITKEASFE YLQNEGERVL LEAMDELEVA FSHPHAKRTD CNHIFLNFVP TVIMDPAKIE 1620
ESVTKMIMRY GPRLWKLRVL QAELKMVIRQ SPQSPTQAVR LCIANDSGYF LDISMYTEQT 1680
EPETGIIKFK AYGEKQGSLH GHPISTPYMT KDFLQQKRFQ AQSNGTTYVY DVPDMFRQMT 1740
ERHWREFSKA RPTVDIRTPD KILIECKELV LEGDNLVEMQ RLPGENNCGM VAWRIVLATP 1800
EYPNGREIIV IANDLTYLIG SFGIKEDVLF AKASQLARQL KVPRIYISVN SGARIGLAEE 1860
VKAMFKIAWE DPEEPDKGFK YLYLSTEDYA QVANLNSVRA ILIEDEGEQR YKITDIIGKD 1920
DGLGVENLRY AGLIAGETSQ AYEEIVTIAM VTCRTIGIGS YVVRLGQRVI QIDNSHIILT 1980
GYAALNKLLG RKVYASNNQL GGTQIMFNNG VTHKTEAIDL DGVYTILDWL SYIPAYIGCD 2040
LPIVLPNDRI ERPVDFMPTK SPYDPRWMLG GRVNPVNAND WENGFFDRDS WSEIMASWAK 2100
TVVTGRARLG GVPVGVIAVE TRTVEVEMPA DPANLDSEAK TLQQAGQVWY PDSSYKTAQA 2160
IKDFGREELP LIVFANWRGF SGGMKDMYEQ IVKFGAYIVD GLREYKKPVL IYLPPNAELR 2220
GGAWAVLDSL INPRYMETYA DPEARGGVLE PEGIVEIKYK EKDLVKTIHR LDPTTIALKK 2280
ELDEANASGD KVRAAQVDEK IKARIAVLMH VYHTVAVHFA DLHDTPERML EKECISEIVP 2340
WRDSRRWLYW RLRRLLLEDA YIKKILRAQD NLSVGQAKQM LRRWLVEEKG ATEAYLWDKN 2400
EEMVSWYEEQ INAESIVSRN VNSVRRDAII STISKMLEDC PDVALDAVVG LCQGLTPVNR 2460
GVVVRTLAQM QLNEETSNSN QG 2482 
Gene Ontology
 GO:0005811; C:lipid particle; IDA:FlyBase.
 GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004075; F:biotin carboxylase activity; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:InterPro.
 GO:0000902; P:cell morphogenesis; IMP:FlyBase.
 GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro. 
Interpro
 IPR013537; AcCoA_COase_cen.
 IPR011761; ATP-grasp.
 IPR013815; ATP_grasp_subdomain_1.
 IPR013816; ATP_grasp_subdomain_2.
 IPR001882; Biotin_BS.
 IPR011764; Biotin_carboxylation_dom.
 IPR005482; Biotin_COase_C.
 IPR000089; Biotin_lipoyl.
 IPR005481; CarbamoylP_synth_lsu_N.
 IPR000022; Carboxyl_trans.
 IPR005479; CbamoylP_synth_lsu-like_ATP-bd.
 IPR011763; COA_CT_C.
 IPR011762; COA_CT_N.
 IPR016185; PreATP-grasp_dom.
 IPR011054; Rudment_hybrid_motif.
 IPR011053; Single_hybrid_motif. 
Pfam
 PF08326; ACC_central
 PF02785; Biotin_carb_C
 PF00364; Biotin_lipoyl
 PF01039; Carboxyl_trans
 PF00289; CPSase_L_chain
 PF02786; CPSase_L_D2 
SMART
 SM00878; Biotin_carb_C 
PROSITE
 PS50975; ATP_GRASP
 PS50979; BC
 PS00188; BIOTIN
 PS50968; BIOTINYL_LIPOYL
 PS50989; COA_CT_CTER
 PS50980; COA_CT_NTER
 PS00866; CPSASE_1
 PS00867; CPSASE_2 
PRINTS