CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024959
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Slc24a2 
Protein Synonyms/Alias
 Slc24a2 protein 
Gene Name
 Slc24a2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
302ISRNNVIKVTVPEAQubiquitination[1]
428AEGRFREKASILHKIubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 711 AA 
Protein Sequence
MDLHQSPTAR LLQKWCSHES PFGCRRHYNS RKKLKLIRVI GLVMGLVAVS TVPFSISAFT 60
ETDSQSNRGE ASDMSGPRVA QGHRQRTLLD LNDKIRDYTP QPPASQEDQA ENSTEHTQGD 120
YPKDIFSLEE RRKGAIILHV IGMIYMFIAL AIVCDEFFVP SLTVITEKLG ISDDVAGATF 180
MAAGGSAPEL FTSLIGVFIA HSNVGIGTIV GSAVFNILFV IGMCALFSRE ILNLTWWPLF 240
RDVSFYIVDL LMLITFFLDN VIMWWESLLL LTAYFAYVVF MKFNVQVERW VKQMISRNNV 300
IKVTVPEAQA KLSEFPPASQ ADGRTACPTI TNDPDCQSLC FEVYPETARH GSCITNVNGE 360
PLKEKTQNSC MEESPTAGDK DGPTLPSKPR LQRGGSSASL HNSLMRNSIF QLMIHTLDPL 420
AEGRFREKAS ILHKIAKKKC QVDENERQNG AANHVEKIEL PNSTSTEVEM TPSSEASEPV 480
QNGNLSHNIE AADAPKATET AEEEDDQPLS LSWPTNTRKQ ATFLIVFPIV FPLWITLPDV 540
RKPASRKFFP ITFFGSITWI AVFSYLMVWW AHQVGETIGI SEEIMGLTIL AAGTSIPDLI 600
TSVIVARKGL GDMAVSSSVG SNIFDITVGL PLPWLLYTII HRFSPVTVSS NGLFCAIVLL 660
FIMLLFVILS IALCKWRMNK ILGFIMFGLY FVFLVVSVLL EDKVLVCPVS I 711 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0016020; C:membrane; IDA:MGI.
 GO:0005262; F:calcium channel activity; IDA:MGI.
 GO:0006874; P:cellular calcium ion homeostasis; IMP:MGI.
 GO:0007612; P:learning; IMP:MGI.
 GO:0060292; P:long term synaptic depression; IMP:MGI.
 GO:0060291; P:long-term synaptic potentiation; IMP:MGI.
 GO:0007613; P:memory; IMP:MGI. 
Interpro
 IPR004481; K/Na/Ca-exchanger.
 IPR004837; NaCa_Exmemb. 
Pfam
 PF01699; Na_Ca_ex 
SMART
  
PROSITE
  
PRINTS