CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044428
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 RANBP2-like and GRIP domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 RGP1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
137CILSTPPKILFCDLRubiquitination[1]
151RLDPGESKSYSYSEVubiquitination[1, 2, 3, 4, 5]
229LEEDEGGKKDSWLAEubiquitination[2, 4]
230EEDEGGKKDSWLAELubiquitination[2, 4]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [5] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 431 AA 
Protein Sequence
MTRALSGLAC RALPAGRDSA EGLGVPIPSV DYARSDSGAA MIEVVAELSR GPVFLAGEAL 60
ECVVTVTNPL PPTATSASSE ALAWASAQIH CQFHASESRV ALPPPDSSQP DVQPDSQTVF 120
LPHRGERGQC ILSTPPKILF CDLRLDPGES KSYSYSEVLP IEGPPSFRGQ SVKYVYKLTI 180
GCQRVNSPIT LLRVPLRVLV LTGLQDVRFP QDEAVAPSSP FLEEDEGGKK DSWLAELAGE 240
RLMAATSCRS LHLYNISDGR GKVGTFGIFK SVYRLGEDVV GTLNLGEGTV ACLQFSVSLQ 300
TEERVQPEYQ RRRGAGGVPS VSHVTHARHQ ESCLHTTRTS FSLPIPLSST PGFCTAIVSL 360
KWRLHFEFVT SREPGLVLLP PVEQPEPTTW TGPEQVPVDT FSWDLPIKVL PTSPTLASYA 420
APGPSTSTIT I 431 
Gene Ontology
  
Interpro
 IPR014848; Rgp1. 
Pfam
 PF08737; Rgp1 
SMART
  
PROSITE
  
PRINTS