| Tag | Content |
|---|
| CPLM ID | CPLM-006831 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | HNRNP arginine N-methyltransferase |
Protein Synonyms/Alias | Protein ODP1 |
Gene Name | HMT1 |
Gene Synonyms/Alias | ODP1; RMT1; YBR034C; YBR0320 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 340 | DGNSRSRKNEGSYLM | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Methylates arginines in a variety of RNA-binding proteins. Methylates NOP3. Can catalyze both the mono- and asymmetric dimethylation. |
Sequence Annotation | BINDING 33 33 S-adenosyl-L-methionine (By similarity).
BINDING 42 42 S-adenosyl-L-methionine (By similarity).
BINDING 66 66 S-adenosyl-L-methionine; via carbonyl
BINDING 88 88 S-adenosyl-L-methionine (By similarity).
BINDING 117 117 S-adenosyl-L-methionine (By similarity). |
Keyword | 3D-structure; Complete proteome; Methyltransferase; Reference proteome; S-adenosyl-L-methionine; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 348 AA |
Protein Sequence | MSKTAVKDSA TEKTKLSESE QHYFNSYDHY GIHEEMLQDT VRTLSYRNAI IQNKDLFKDK 60
IVLDVGCGTG ILSMFAAKHG AKHVIGVDMS SIIEMAKELV ELNGFSDKIT LLRGKLEDVH 120
LPFPKVDIII SEWMGYFLLY ESMMDTVLYA RDHYLVEGGL IFPDKCSIHL AGLEDSQYKD 180
EKLNYWQDVY GFDYSPFVPL VLHEPIVDTV ERNNVNTTSD KLIEFDLNTV KISDLAFKSN 240
FKLTAKRQDM INGIVTWFDI VFPAPKGKRP VEFSTGPHAP YTHWKQTIFY FPDDLDAETG 300
DTIEGELVCS PNEKNNRDLN IKISYKFESN GIDGNSRSRK NEGSYLMH 348 |
Gene Ontology | GO:0005634; C:nucleus; IDA:SGD. GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; IMP:SGD. GO:0035241; F:protein-arginine omega-N monomethyltransferase activity; IDA:SGD. GO:0006406; P:mRNA export from nucleus; IGI:SGD. GO:0060567; P:negative regulation of DNA-dependent transcription, termination; IMP:SGD. GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IMP:SGD. |
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