UniProt Accession

 H0VM26_CAVPO; H0VM26 

Genbank Protein ID

 AAKN02020173 

Genbank Nucleotide ID

  

Protein Name

 ATP synthase subunit alpha 

Protein Synonyms/Alias

  

Gene Name

 LOC100729830 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Cavia porcellus (Guinea pig) 

NCBI Taxa ID

 10141 

Lysine Modification

Position	Peptide	Type	References
120	VVVFGNDKLIKEGDI	acetylation	[1]
158	LGNAIDGKGPIGSKT	acetylation	[1]
236	FNDGSDEKKKLYCIY	acetylation	[1]
237	NDGSDEKKKLYCIYV	acetylation	[1]
238	DGSDEKKKLYCIYVA	acetylation	[1]
258	STVAQLVKRLTDADA	acetylation	[1]
424	AAQTRAMKQVAGTMK	acetylation	[1]
495	GVRGYLDKLEPSKIT	acetylation	[1]
503	LEPSKITKFEQAFLS	acetylation	[1]
528	GTIRADGKISEQSDA	acetylation	[1]
536	ISEQSDAKLKEIVTN	acetylation	[1]
538	EQSDAKLKEIVTNFL	acetylation	[1]

Reference

 [1] The cardiac acetyl-lysine proteome.
 Foster DB, Liu T, Rucker J, O'Meally RN, Devine LR, Cole RN, O'Rourke B.
 PLoS One. 2013;8(7):e67513. [PMID: 23844019] 

Functional Description

 Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity). 

Sequence Annotation

  

Keyword

 ATP synthesis; ATP-binding; CF(1); Complete proteome; Hydrogen ion transport; Ion transport; Nucleotide-binding; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 550 AA 

Protein Sequence

Gene Ontology

 GO:0005753; C:mitochondrial proton-transporting ATP synthase complex; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0045261; C:proton-transporting ATP synthase complex, catalytic core F(1); IEA:UniProtKB-KW.
 GO:0008180; C:signalosome; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:Compara.
 GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
 GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
 GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro.
 GO:0009790; P:embryo development; IEA:Compara.
 GO:0006629; P:lipid metabolic process; IEA:Compara.
 GO:0001937; P:negative regulation of endothelial cell proliferation; IEA:Compara. 

Interpro

 IPR020003; ATPase_a/bsu_AS.
 IPR004100; ATPase_a/bsu_N.
 IPR005294; ATPase_F1-cplx_asu.
 IPR023366; ATPase_F1/A1-cplx_a_su_N.
 IPR000793; ATPase_F1/V1/A1-cplx_a/bsu_C.
 IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd.
 IPR027417; P-loop_NTPase. 

Pfam

 PF00006; ATP-synt_ab
 PF00306; ATP-synt_ab_C
 PF02874; ATP-synt_ab_N 

SMART

  

PROSITE

 PS00152; ATPASE_ALPHA_BETA 

PRINTS