CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025249
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 Amfr 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
353DSMQAARKLPCGHLFubiquitination[1]
573ARGSRFSKSADERQRubiquitination[1]
586QRMLVQRKDDLLQQAubiquitination[1]
600ARKRFLNKSSEDDGAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Metal-binding; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 643 AA 
Protein Sequence
MPLLFLERFP WPSLRTYTGL SGLALLGTIV SAYRALSQPE DGSGEPEPLT APLQPEALAP 60
ARLTAGGPRA RDVAQYLLSD SLFVWVLVNT ACCVLMLVAK LIQCIVFGPL RVSERQHLKD 120
KFWNFIFYKF IFIFGVLNVQ TVEEVVMWCL WFAGLVFLHL MVQLCKDRFE YLSFSPTTPM 180
SSHGRVLSLL IAMLLSCCGL AVVCCVTGYT HGMHTLAFMA AESLLVTVRT AHVILRYVIH 240
LWDLNHEGTW EGKGTYVYYT DFVMELALLS LDLMHHIHML LFGNIWLSMA SLVIFMQLRY 300
LFHEVQRRIR RHKNYLRVVG NMEARFAVAT PEELAVNNDD CAICWDSMQA ARKLPCGHLF 360
HNSCLRSWLE QDTSCPTCRM SLNIADGSRA REDHQGENLD ENLVPVAAAE GRPRLNQHNH 420
FFHFDGSRIA SWLPSFSVEV MHTTNILGIT QASNSQLNAM AHQIQEMFPQ VPYHLVLQDL 480
QMTRSVEITT DNILEGRIQV PFPTQRSDSL RPALNSPVER PSPDLEEGEA SVQTERVPLD 540
LSPRLEETLD FSEVELEPIE VEDFEARGSR FSKSADERQR MLVQRKDDLL QQARKRFLNK 600
SSEDDGASER LLPSEGTSSD PVTLRRRMLA AAAERRLQRQ RTT 643 
Gene Ontology
 GO:0030176; C:integral to endoplasmic reticulum membrane; IEA:Compara.
 GO:0005887; C:integral to plasma membrane; ISS:MGI.
 GO:0004872; F:receptor activity; IEA:Compara.
 GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0009987; P:cellular process; TAS:MGI.
 GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:Compara.
 GO:0030433; P:ER-associated protein catabolic process; IEA:Compara.
 GO:0051259; P:protein oligomerization; IEA:Compara.
 GO:0000209; P:protein polyubiquitination; IEA:Compara. 
Interpro
 IPR026608; Amfr.
 IPR003892; CUE.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF02845; CUE
 PF13639; zf-RING_2 
SMART
 SM00546; CUE
 SM00184; RING 
PROSITE
 PS51140; CUE
 PS50089; ZF_RING_2 
PRINTS