CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043273
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 ATP-dependent RNA helicase DDX19B 
Protein Synonyms/Alias
  
Gene Name
 DDX19B 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
51AAQSLLNKLIRSNLVubiquitination[1, 2]
79NSPLYSVKSFEELRLubiquitination[1, 2, 3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 233 AA 
Protein Sequence
MQLREKLSNL HLKEEKIKPD TNGAVVKTNA NAEKTDEEEK EDRAAQSLLN KLIRSNLVDN 60
TNQVEVLQRD PNSPLYSVKS FEELRLKPQL LQGVYAMGFN RPSKIQENAL PLMLAEPPQN 120
LIAQSQSGTG KTAAFVLAML SQVEPANKYP QCLCLSPTYE LALQTGKVIE QMGKFYPELK 180
LAYAVRGNKL ERGQKISEQI VIGTPGTVLD WCSKLKFIDP KKIKVFVLDE ADV 233 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 
Interpro
 IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
 IPR014001; Helicase_ATP-bd.
 IPR027417; P-loop_NTPase.
 IPR014014; RNA_helicase_DEAD_Q_motif. 
Pfam
 PF00270; DEAD 
SMART
 SM00487; DEXDc 
PROSITE
 PS51192; HELICASE_ATP_BIND_1
 PS51195; Q_MOTIF 
PRINTS