CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033833
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 B-cell lymphoma/leukemia 11B 
Protein Synonyms/Alias
  
Gene Name
 BCL11B 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
233PQPPAKSKSCEFCGKubiquitination[1, 2]
240KSCEFCGKTFKFQSNacetylation[2]
240KSCEFCGKTFKFQSNubiquitination[1, 2]
243EFCGKTFKFQSNLIVubiquitination[1]
262HTGEKPYKCQLCDHAubiquitination[1]
275HACSQASKLKRHMKTubiquitination[1, 2]
277CSQASKLKRHMKTHMubiquitination[1]
391GAGGGAAKALADEKAubiquitination[1, 2]
397AKALADEKALVLGKVubiquitination[1, 2, 3]
403EKALVLGKVMENVGLubiquitination[2]
423YGELLADKQKRGAFLubiquitination[1, 2, 3]
425ELLADKQKRGAFLKRubiquitination[1, 2]
431QKRGAFLKRAAGGGDubiquitination[1]
478FPGLFPRKPAPLPSPubiquitination[1, 2, 3]
492PGLNSAAKRIKVEKDubiquitination[1, 2, 3]
529AASRHFMKDPFLGFTubiquitination[1, 2, 3]
596GPGRPSSKEGRRSDTubiquitination[1, 2]
609DTCEYCGKVFKNCSNubiquitination[1, 2, 3]
612EYCGKVFKNCSNLTVubiquitination[1, 2]
631HTGERPYKCELCNYAubiquitination[1, 2]
644YACAQSSKLTRHMKTubiquitination[1, 2, 3]
657KTHGQIGKEVYRCDIubiquitination[1, 2]
677SVYSTLEKHMKKWHGubiquitination[1]
680STLEKHMKKWHGEHLubiquitination[1]
681TLEKHMKKWHGEHLLubiquitination[1, 2]
693HLLTNDVKIEQAERSubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 700 AA 
Protein Sequence
MSRRKQGNPQ HLSQRELITR KDEPSSYICT TCKQPFNSAW FLLQHAQNTH GFRIYLEPGP 60
ASSSLTPRLT IPPPLGPEAV AQSPLMNFLG DSNPFNLLRM TGPILRDHPG FGEGRLPGTP 120
PLFSPPPRHH LDPHRLSAEE MGLVAQHPSA FDRVMRLNPM AIDSPAMDFS RRLRELAGNS 180
STPPPVSPGR GNPMHRLLNP FQPSPKSPFL STPPLPPMPP GGTPPPQPPA KSKSCEFCGK 240
TFKFQSNLIV HRRSHTGEKP YKCQLCDHAC SQASKLKRHM KTHMHKAGSL AGRSDDGLSA 300
ASSPEPGTSE LAGEGLKAAD GDFRHHESDP SLGHEPEEED EEEEEEEEEL LLENESRPES 360
SFSMDSELSR NRENGGGGVP GVPGAGGGAA KALADEKALV LGKVMENVGL GALPQYGELL 420
ADKQKRGAFL KRAAGGGDAG DDDDAGGCGD AGAGGAVNGR GGGFAPGTEP FPGLFPRKPA 480
PLPSPGLNSA AKRIKVEKDL ELPPAALIPS ENVYSQWLVG YAASRHFMKD PFLGFTDARQ 540
SPFATSSEHS SENGSLRFST PPGDLLDGGL SGRSGTASGG STPHLGGPGP GRPSSKEGRR 600
SDTCEYCGKV FKNCSNLTVH RRSHTGERPY KCELCNYACA QSSKLTRHMK THGQIGKEVY 660
RCDICQMPFS VYSTLEKHMK KWHGEHLLTN DVKIEQAERS 700 
Gene Ontology
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF00096; zf-C2H2 
SMART
 SM00355; ZnF_C2H2 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS