Tag | Content |
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CPLM ID | CPLM-001073 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Vesicle-associated membrane protein 4 |
Protein Synonyms/Alias | VAMP-4 |
Gene Name | Vamp4 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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19 | DDVTGSVKSERRNLL | ubiquitination | [1] | 87 | RLDELQDKSESLSDN | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule (By similarity). |
Sequence Annotation | DOMAIN 52 112 v-SNARE coiled-coil homology. MOD_RES 17 17 Phosphoserine. MOD_RES 30 30 Phosphoserine. |
Keyword | 3D-structure; Coiled coil; Complete proteome; Golgi apparatus; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 141 AA |
Protein Sequence | MPPKFKRHLN DDDVTGSVKS ERRNLLEDDS DEEEDFFLRG PSGPRFGPRN DKIKHVQNQV 60 DEVIDVMQEN ITKVIERGER LDELQDKSES LSDNATAFSN RSKQLRRQMW WRGCKIKAIM 120 ALAAAILLLM IIILIVVKFR T 141 |
Gene Ontology | GO:0005794; C:Golgi apparatus; IDA:MGI. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0031201; C:SNARE complex; IDA:MGI. GO:0005802; C:trans-Golgi network; IDA:MGI. GO:0043001; P:Golgi to plasma membrane protein transport; IMP:MGI. GO:0042996; P:regulation of Golgi to plasma membrane protein transport; IMP:MGI. |
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PRINTS | |