UniProt Accession

 WDR73_HUMAN; Q6P4I2; Q96JZ1; Q9P0B7 

Genbank Protein ID

 AF161382; AK027794; BC063392 

Genbank Nucleotide ID

 AAF28942.1; BAB55373.1; AAH63392.1 

Protein Name

 WD repeat-containing protein 73 

Protein Synonyms/Alias

  

Gene Name

 WDR73 

Gene Synonyms/Alias

 HSPC264 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
55	KNEILHLKLPLRLSV	ubiquitination	[1]
63	LPLRLSVKENKGLFP	ubiquitination	[2]
66	RLSVKENKGLFPERD	ubiquitination	[2]
90	DRSIFDLKHVPHTRL	ubiquitination	[1]
208	GLVDTRQKWAPLENR	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

 REPEAT 81 121 WD 1.
 REPEAT 273 313 WD 2.
 REPEAT 339 378 WD 3.  

Keyword

 Complete proteome; Polymorphism; Reference proteome; Repeat; WD repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 378 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 

Pfam

  

SMART

 SM00320; WD40 

PROSITE

 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 

PRINTS