| Tag | Content |
|---|
| CPLM ID | CPLM-016528 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | ADP-ribosylation factor-binding protein GGA3 |
Protein Synonyms/Alias | Golgi-localized, gamma ear-containing, ARF-binding protein 3 |
Gene Name | Gga3 |
Gene Synonyms/Alias | Kiaa0154 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 15 | SLESWLNKATNPSNR | ubiquitination | [1] | | 258 | LFDRCENKRRTLFKL | ubiquitination | [1] | | 264 | NKRRTLFKLASETED | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif (By similarity). |
Sequence Annotation | DOMAIN 16 146 VHS.
DOMAIN 171 298 GAT.
DOMAIN 589 710 GAE.
REGION 299 588 Unstructured hinge.
MOTIF 387 391 Autoinhibitory (By similarity). |
Keyword | Complete proteome; Endosome; Golgi apparatus; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transport; Ubl conjugation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 718 AA |
Protein Sequence | MAEAEGESLE SWLNKATNPS NRQEDWEYII GFCDQINKEL EGPQIAVRLL AHKIQSPQEW 60
EAVQALTVLE ACMKNCGRRL HNEVGKFRFL NELIKVVSPK YLGDRVSEKV KTKVIELLFS 120
WTLALPEEAK IKDAYHMLKR QGIVQSDPPI PMDRTLIPSP PPRPKNPVFD DEEKSKLLAR 180
LLKSKNPDDL QEANRLIKSM VKEDEARIQK VTKRLHTLEE VNNNVKLLHE MLLHYSQEYS 240
SDADKELMKE LFDRCENKRR TLFKLASETE DNDNSLGDIL QASDNLSRVI NSYKTIIEGQ 300
IVNGEVTTST MPDSEGNSHC GNQGALIDLA ELDAPSNSSP ALAPPTSGIP ILPPPPQTSG 360
PPRSRSSSQA EAPPGSDSTN NALSLLDEEL LCLGLTDPAP TAPKESPGSS QWHLFQNEPP 420
SDLDFFSPRP VPAASCPSDG PQLPPPVSTS SMSQAPLPAA FPAPVVPASA PTHSTGSFMF 480
SSGPAPALAP KAEPKGPEYP SSSTSHRLDA LDQLLEEAKV TSGLVKPVSC FSPGPTASPL 540
LPASAPARPL LPFSTGPGSP LFQSQGSPQK GPELSLASVH VPLESIKPSS ALPVTAYDKN 600
GFRILFHFAK ECPPGRPDVL VVVVSMLNTA PLPVKSIVLQ AAVPKSMKVK LQPPSGTELS 660
PFSPIQPPAA ITQVMLLANP MKEKVRLRYK LTFALGEQLS TELGEVDQFP PVEQWGNL 718 |
Gene Ontology | GO:0030131; C:clathrin adaptor complex; IEA:InterPro. GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. GO:0005802; C:trans-Golgi network; IEA:Compara. GO:0006886; P:intracellular protein transport; IEA:InterPro. GO:0045732; P:positive regulation of protein catabolic process; IGI:MGI. GO:0016192; P:vesicle-mediated transport; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |