CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037024
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Macrophage erythroblast attacher 
Protein Synonyms/Alias
  
Gene Name
 MAEA 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
23VQEYPTLKVPYETLNubiquitination[1]
31VPYETLNKRFRAAQKubiquitination[1]
82VEKLSVLKRKAVESIubiquitination[1]
84KLSVLKRKAVESIQAubiquitination[1]
97QAEDESAKLCKRRIEubiquitination[1]
107KRRIEHLKEHSSDQPubiquitination[1]
121PAAASVWKRKRMDRMubiquitination[1]
144GYYNTAVKLARQSGIubiquitination[1]
186LAWCHDNKSRLRKMKubiquitination[1]
261DAVRHARKHFSQAEGubiquitination[1]
342IKTPQCYKEDGSSKSubiquitination[1]
348YKEDGSSKSPDCPVCubiquitination[1]
361VCSRSLNKLAQPLPMubiquitination[1]
413LSIRQDDKVVCPRTKubiquitination[1]
420KVVCPRTKEVFHFSQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 434 AA 
Protein Sequence
MAVQESAAQL SMTLKVQEYP TLKVPYETLN KRFRAAQKNI DRETSHVTMV VAELEKTLSG 60
CPAVDSVVSL LDGVVEKLSV LKRKAVESIQ AEDESAKLCK RRIEHLKEHS SDQPAAASVW 120
KRKRMDRMMV EHLLRCGYYN TAVKLARQSG IEDLVNIEMF LTAKEVEESL ERRETATCLA 180
WCHDNKSRLR KMKGRQNKHE AKTGRKSRAA SSSPKESLDL GMETLKGKPE LSCLEFSLRI 240
QEFIELIRQN KRLDAVRHAR KHFSQAEGSQ LDEVRQAMGM LAFPPDTHIS PYKDLLDPAR 300
WRMLIQQFRY DNYRLHQLGN NSVFTLTLQA GLSAIKTPQC YKEDGSSKSP DCPVCSRSLN 360
KLAQPLPMAH CANSRLVCKI SGDVMNENNP PMMLPNGYVY GYNSLLSIRQ DDKVVCPRTK 420
EVFHFSQAEK VYIM 434 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
 IPR013144; CRA_dom.
 IPR024964; CTLH/CRA.
 IPR006595; CTLH_C.
 IPR006594; LisH_dimerisation.
 IPR027370; zf-RING_LisH. 
Pfam
 PF10607; CLTH
 PF13445; zf-RING_LisH 
SMART
 SM00757; CRA
 SM00668; CTLH
 SM00667; LisH 
PROSITE
 PS50897; CTLH
 PS50896; LISH 
PRINTS