UniProt Accession

 S10AA_RAT; P05943; Q5BJ98 

Genbank Protein ID

 J03627; AF465254; BC091565 

Genbank Nucleotide ID

 AAA42097.1; AAO33353.1; AAH91565.1 

Protein Name

 Protein S100-A10 

Protein Synonyms/Alias

 Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; Nerve growth factor-induced protein 42C; S100 calcium-binding protein A10; p10 protein; p11 

Gene Name

 S100a10 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
23	FHRFAGEKNYLTKED	acetylation	[1]
28	GEKNYLTKEDLRVLM	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase (By similarity). 

Sequence Annotation

 REGION 60 71 Ancestral calcium site.
 MOD_RES 23 23 N6-acetyllysine (By similarity).
 MOD_RES 28 28 N6-acetyllysine (By similarity).
 MOD_RES 54 54 N6-acetyllysine (By similarity).
 MOD_RES 57 57 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; Complete proteome; Direct protein sequencing; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 95 AA 

Protein Sequence

Gene Ontology

 GO:0005783; C:endoplasmic reticulum; IDA:RGD.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0045595; P:regulation of cell differentiation; NAS:RGD.
 GO:0001558; P:regulation of cell growth; NAS:RGD. 

Interpro

 IPR011992; EF-hand-like_dom.
 IPR002048; EF_hand_dom.
 IPR001751; S100/CaBP-9k_CS.
 IPR013787; S100_Ca-bd_sub. 

Pfam

 PF01023; S_100 

SMART

  

PROSITE

 PS50222; EF_HAND_2
 PS00303; S100_CABP 

PRINTS