UniProt Accession

 HMGN2_RAT; P18437 

Genbank Protein ID

  

Genbank Nucleotide ID

  

Protein Name

 Non-histone chromosomal protein HMG-17 

Protein Synonyms/Alias

 High mobility group nucleosome-binding domain-containing protein 2 

Gene Name

 Hmgn2 

Gene Synonyms/Alias

 Hmg-17; Hmg17 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
40	APPKPEPKPKKAPAK	acetylation	[1]
59	VPKGKKGKADAGKDA	acetylation	[1]
64	KGKADAGKDANNPAE	acetylation	[1]
76	PAEDGDAKTDQAQKA	acetylation	[1]
82	AKTDQAQKADGAGDA	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation (By similarity). 

Sequence Annotation

 MOD_RES 25 25 Phosphoserine (By similarity).
 MOD_RES 29 29 Phosphoserine (By similarity).
 MOD_RES 82 82 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; DNA-binding; Nucleus; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 90 AA 

Protein Sequence

Gene Ontology

 GO:0000785; C:chromatin; IEA:InterPro.
 GO:0005694; C:chromosome; TAS:RGD.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0031492; F:nucleosomal DNA binding; IEA:InterPro. 

Interpro

 IPR000079; HMGN_fam. 

Pfam

 PF01101; HMG14_17 

SMART

 SM00527; HMG17 

PROSITE

 PS00355; HMG14_17 

PRINTS

 PR00925; NONHISHMG17.