CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007822
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ankyrin repeat-containing protein YAR1 
Protein Synonyms/Alias
  
Gene Name
 YAR1 
Gene Synonyms/Alias
 YPL239W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
125ADPFIRNKFGHDAIFacetylation[1]
166EDTQTEGKNSVQITKubiquitination[2]
173KNSVQITKGTEIEQVubiquitination[2]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Required for normal rate of cell proliferation. 
Sequence Annotation
 REPEAT 49 78 ANK 1.
 REPEAT 92 121 ANK 2.
 MOD_RES 78 78 Phosphoserine.  
Keyword
 ANK repeat; Complete proteome; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 200 AA 
Protein Sequence
MGLHSEPLDQ EDQDTIILDA RAGDLDSLKD IFTTLVSPEL LSTCKESESD STALHMAAAN 60
GHIETVRYIL ETVSRANSAE DLKAFVNEVN KTGNTALHWA SLNGKLDVVK LLCDEYEADP 120
FIRNKFGHDA IFEAENSGKE EVETYFLKKY DVEPEDDEED TQTEGKNSVQ ITKGTEIEQV 180
TKEATEALRE ETEKLNINKD 200 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0051082; F:unfolded protein binding; IMP:SGD.
 GO:0034599; P:cellular response to oxidative stress; IMP:SGD.
 GO:0032880; P:regulation of protein localization; IMP:SGD.
 GO:0006970; P:response to osmotic stress; IMP:SGD.
 GO:0042274; P:ribosomal small subunit biogenesis; IMP:SGD.
 GO:0000056; P:ribosomal small subunit export from nucleus; IMP:SGD. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom. 
Pfam
 PF12796; Ank_2 
SMART
 SM00248; ANK 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT 
PRINTS