| Tag | Content |
|---|
| CPLM ID | CPLM-001400 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | 26S proteasome non-ATPase regulatory subunit 1 |
Protein Synonyms/Alias | 26S proteasome regulatory subunit RPN2; 26S proteasome regulatory subunit S1; 26S proteasome subunit p112 |
Gene Name | Psmd1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 302 | DSMETEEKTAGAVAG | ubiquitination | [1] | | 310 | TAGAVAGKTPDASPE | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (By similarity). |
Sequence Annotation | REPEAT 403 436 PC 1.
REPEAT 441 474 PC 2.
REPEAT 476 510 PC 3.
REPEAT 511 545 PC 4.
REPEAT 547 580 PC 5.
REPEAT 581 616 PC 6.
REPEAT 617 649 PC 7.
REPEAT 651 685 PC 8.
REPEAT 686 726 PC 9.
REPEAT 729 761 PC 10.
MOD_RES 1 1 N-acetylmethionine (By similarity).
MOD_RES 273 273 Phosphothreonine (By similarity).
MOD_RES 310 310 N6-acetyllysine (By similarity).
MOD_RES 311 311 Phosphothreonine (By similarity).
MOD_RES 315 315 Phosphoserine (By similarity). |
Keyword | Acetylation; Complete proteome; Phosphoprotein; Proteasome; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 953 AA |
Protein Sequence | MITSAAGIIS LLDEEEPQLK EFALHKLNAV VNDFWAEISE SVDKIEVLYE DEGFRSRQFA 60
ALVASKVFYH LGAFEESLNY ALGAGDLFNV NDNSEYVETI IAKCIDHYTK QCVENADLPE 120
GEKKPIDQRL EGIVNKMFQR CLDDHKYKQA IGIALETRRL DVFEKTILES NDVPGMLAYS 180
LKLCMSLMQN KQFRNKVLRV LVKIYMNLEK PDFINVCQCL IFLDDTQAVS DILEKLVKED 240
NLLMAYQICF DLYESASQQF LSSVIQNLRT VGTPIASVPG STNTGTVPGP EKDSDSMETE 300
EKTAGAVAGK TPDASPEPKD QTLKMIKILS GEMAIELHLQ FLIRNNNTDL MILKNTKDAV 360
RNSVCHTATV IANSFMHCGT TSDQFLRDNL EWLARATNWA KFTATASLGV IHKGHEKEAL 420
QLMATYLPKD TSPGSAYQEG GGLYALGLIH ANHGGDIIDY LLNQLKNASN DIVRHGGSLG 480
LGLAAMGTAR QDVYDLLKTN LYQDDAVTGE AAGLALGLVM LGSKNTQAIE DMVGYAQETQ 540
HEKILRGLAV GIALVMYGRM EEADALIESL CRDKDPILRR SGMYTVAMAY CGSGNNKAIR 600
RLLHVAVSDV NDDVRRAAVE SLGFILFRTP EQCPSVVSLL SESYNPHVRY GAAMALGVCC 660
AGTGNKEAIN LLEPMTNDPV NYVRQGALIA SALIMIQQTE ITCPKVNQFR QLYSKVINDK 720
HDDVMAKFGA ILAQGILDAG GHNVTISLQS RTGHTHMPSV VGVLVFTQFW FWFPLSHFLS 780
LAYTPTCIIG LNKDLKMPKV QYKSNCKPST FAYPAPLEVP KEKEKEKVST AVLSITAKAK 840
KKEKEKEKKE EEKMEVDEAE KKEEKEKKKE PEPNFQLLDN PARVMPAQLK VLSMTETCRY 900
QPFKPLSIGG IIILKDTSED IEELVEPVAA HGPKIEEEEQ EPEPPEPFEY IDD 953 |
Gene Ontology | GO:0022624; C:proteasome accessory complex; ISS:UniProtKB. GO:0030234; F:enzyme regulator activity; IEA:InterPro. GO:0050790; P:regulation of catalytic activity; IEA:GOC. GO:0042176; P:regulation of protein catabolic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |