| Tag | Content |
|---|
| CPLM ID | CPLM-018090 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 721 |
Protein Synonyms/Alias | |
Gene Name | ZNF721 |
Gene Synonyms/Alias | KIAA1982 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 319 | RRIHTGEKPYTCGEC | ubiquitination | [1] | | 347 | RRIHTGEKPYKCEDC | ubiquitination | [1] | | 350 | HTGEKPYKCEDCGKA | ubiquitination | [1] | | 658 | LTGEQSYKCEECGKA | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation (By similarity). |
Sequence Annotation | ZN_FING 69 91 C2H2-type 1; degenerate.
ZN_FING 97 119 C2H2-type 2.
ZN_FING 125 147 C2H2-type 3; degenerate.
ZN_FING 153 175 C2H2-type 4.
ZN_FING 181 203 C2H2-type 5; degenerate.
ZN_FING 209 231 C2H2-type 6.
ZN_FING 237 259 C2H2-type 7.
ZN_FING 265 287 C2H2-type 8.
ZN_FING 293 315 C2H2-type 9.
ZN_FING 321 343 C2H2-type 10.
ZN_FING 349 371 C2H2-type 11.
ZN_FING 377 399 C2H2-type 12.
ZN_FING 405 427 C2H2-type 13; degenerate.
ZN_FING 433 455 C2H2-type 14.
ZN_FING 461 483 C2H2-type 15.
ZN_FING 489 511 C2H2-type 16.
ZN_FING 517 539 C2H2-type 17.
ZN_FING 545 567 C2H2-type 18.
ZN_FING 573 595 C2H2-type 19.
ZN_FING 601 623 C2H2-type 20; degenerate.
ZN_FING 629 651 C2H2-type 21; degenerate.
ZN_FING 657 679 C2H2-type 22.
ZN_FING 685 707 C2H2-type 23.
ZN_FING 713 735 C2H2-type 24; degenerate.
ZN_FING 741 763 C2H2-type 25.
ZN_FING 769 791 C2H2-type 26.
ZN_FING 797 819 C2H2-type 27.
ZN_FING 825 847 C2H2-type 28.
ZN_FING 853 875 C2H2-type 29.
ZN_FING 881 903 C2H2-type 30. |
Keyword | Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 911 AA |
Protein Sequence | MCSHFTQDFL PVQGIEDSFH KLILRRYEKC GHDNLQLRKG CKSMNVCKVQ KGVYNGINKC 60
LSNTQSKIFQ CNARVKVFSK FANSNKDKTR HTGEKHFKCN ECGKSFQKFS DLTQHKGIHA 120
GEKPYTCEER GKDFGWYTDL NQHKKIHTGE KPYKCEECGK AFNRSTNLTA HKRIHNREKA 180
YTGEDRDRAF GWSTNLNEYK KIHTGDKPYK CKECGKAFMH SSHLNKHEKI HTGEKPYKCK 240
ECGKVISSSS SFAKHKRIHT GEKPFKCLEC GKAFNISTTL TKHRRIHTGE KPYTCEVCGK 300
AFRQSANLYV HRRIHTGEKP YTCGECGKTF RQSANLYVHR RIHTGEKPYK CEDCGKAFGR 360
YTALNQHKKI HTGEKPYKCE ECGKAFNSST NLTAHKRIHT REKPYTCEDR GRAFGLSTNL 420
NEYKKIHTGD KPYKCKECGK AFIHSLHLNK HEKIHTGKKP YKCKQCGKVI TSSSSFAKHK 480
RIHTGEKPFE CLECGKAFTS STTLTKHRRI HTGEKPYTCE VCGKAFRQSA ILYVHRRIHT 540
GEKPYTCEEC GKTFRQSANL YVHRRIHTGE KPYKCEECGK AFGRYTDLNQ HKKIHTGEKL 600
YKCEECGKDF VWYTDLNQQK KIYTGEKPYK CEECGKAFAP STDLNQHTKI LTGEQSYKCE 660
ECGKAFGWSI ALNQHKKIHT GEKPYKCEEC GKAFSRSRNL TTHRRVHTRE KPYKCEDRGR 720
SFGWSTNLNE YKKIHTGDKL YKCKECGKVF KQSSHLNRHE KIHTGKKPYK CKECGKVITS 780
SSSFAKHKRI HTGEKPFKCL ECGKAFTSST TLTKHRRIHT GEKPYTCEEC GKAFRQSAIL 840
YVHRRIHTGE KPYTCGECGK TFRQSANLYA HKKIHTGEKP YTCGDCGKTF RQSANLYAHK 900
KIHTGDKTIQ V 911 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |