Tag | Content |
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CPLM ID | CPLM-017269 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Calcium-binding mitochondrial carrier protein SCaMC-2 |
Protein Synonyms/Alias | Mitochondrial ATP-Mg/Pi carrier protein; Peroxisomal Ca(2+)-dependent solute carrier-like protein; Small calcium-binding mitochondrial carrier protein 2; Solute carrier family 25 member 25 |
Gene Name | Slc25a25 |
Gene Synonyms/Alias | Mcsc; Pcscl; Scamc2 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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329 | CAKRILAKEGVAAFY | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria (By similarity). |
Sequence Annotation | DOMAIN 47 80 EF-hand 1. DOMAIN 78 113 EF-hand 2. DOMAIN 114 149 EF-hand 3. REPEAT 184 270 Solcar 1. REPEAT 278 363 Solcar 2. REPEAT 375 463 Solcar 3. |
Keyword | Calcium; Complete proteome; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 469 AA |
Protein Sequence | MLCLCLYVPI AGEAQTEFQY FESKGLPTEL KSIFKLSVFI PSQEFSTYRQ WKQKIVQAGD 60 KDLDGQLDFE EFVHYLQDHE KKLRLVFKSL DKKNDGRIDA QEIMQSLRDL GVKISEQQAE 120 KILKSMDKNG TMTIDWNEWR DYHLLHPVEN IPEIILYWKH STIFDVGENL TVPDEFTVEE 180 RQTGMWWRHL VAGGGAGAVS RTCTAPLDRL KVLMQVHASR SNNMCIIGGF TQMIREGGAK 240 SLWRGNGINV LKIAPESAIK FMAYEQMKRL VGSDQETLRI HERLVAGSLA GAIAQSSIYP 300 MEVLKTRMAL RKTGQYSGML DCAKRILAKE GVAAFYKGYI PNMLGIIPYA GIDLAVYETL 360 KNTWLQRYAV NSADPGVFVL LACGTISSTC GQLASYPLAL VRTRMQAQAS IEGAPEVTMS 420 SLFKQILRTE GAFGLYRGLA PNFMKVIPAV SISYVVYENL KITLGVQSR 469 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. GO:0005509; F:calcium ion binding; IEA:InterPro. GO:0055085; P:transmembrane transport; IEA:InterPro. |
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