CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028930
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Aldo-keto reductase family 1, member C12-like 1 
Protein Synonyms/Alias
 Protein Akr1c12l1 
Gene Name
 Akr1c12l1 
Gene Synonyms/Alias
 Akr1c12; RGD1559604 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
161CKDAGLVKSIGVSNFacetylation[1]
171GVSNFNHKQLERLLNacetylation[1]
301KTLDGLNKNFRYLSAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 ACT_SITE 55 55 Proton donor (By similarity).  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 323 AA 
Protein Sequence
MSSKHHCVKL NDGHFIPALG FGTSIPNEVP KSKSLEAVHL AIDAGYHHID TASAYQIEEE 60
IGQAIQSKIK AGVVKREDMF ITTKLWCTCF RPELVKPALE KSLKNLQLDY ADLYIMHYPV 120
PMKSGDKYLP VDDKGKWLLD TVDFCDTWEM LEKCKDAGLV KSIGVSNFNH KQLERLLNKP 180
GLKYKPVCNQ VECHLYMNQS KLLDYCKSKD IVLVAYGALG TQRYKEWVDQ NSPVLLDDPV 240
LCDVAKKNKR SPALIALRYL VQREVVPLAQ SFKENEMREN LQVFEFQLSP EDMKTLDGLN 300
KNFRYLSAEF LAGHPEYPFS EEY 323 
Gene Ontology
 GO:0016491; F:oxidoreductase activity; IEA:InterPro. 
Interpro
 IPR001395; Aldo/ket_red.
 IPR018170; Aldo/ket_reductase_CS.
 IPR020471; Aldo/keto_reductase_subgr.
 IPR023210; NADP_OxRdtase_dom. 
Pfam
 PF00248; Aldo_ket_red 
SMART
  
PROSITE
 PS00062; ALDOKETO_REDUCTASE_2 
PRINTS
 PR00069; ALDKETRDTASE.