CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031350
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transporter 
Protein Synonyms/Alias
  
Gene Name
 SLC6A2 
Gene Synonyms/Alias
 hCG_2025341 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
99GNHTKYSKYKFTPAAubiquitination[1]
101HTKYSKYKFTPAAEFubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Symport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 512 AA 
Protein Sequence
MGVQWWSHTQ GEVAVGLGLG DSYLTPCPCP GVGYAVILIA LYVGFYYNVI IAWSLYYLFS 60
SFTLNLPWTD CGHTWNSPNC TDPKLLNGSV LGNHTKYSKY KFTPAAEFYE RGVLHLHESS 120
GIHDIGLPQW QLLLCLMVVV IVLYFSLWKG VKTSGKVVWI TATLPYFVLF VLLVHGVTLP 180
GASNGINAYL HIDFYRLKEA TVWIDAATQI FFSLGAGFGV LIAFASYNKF DNNCYRDALL 240
TSSINCITSF VSGFAIFSIL GYMAHEHKVN IEDVATEGAG LVFILYPEAI STLSGSTFWA 300
VVFFVMLLAL GLDSSMGGME AVITGLADDF QVLKRHRKLF TFGVTFSTFL LALFCITKGG 360
IYVLTLLDTF AAGTSILFAV LMEAIGVSWF YGVDRFSNDI QQMMGFRPGL YWRLCWKFVS 420
PAFLLFVVVV SIINFKPLTY DDYIFPPWAN WVGWGIALSS MVLVPIYVIY KFLSTQGSLW 480
ERLAYGITPE NEHHLVAQRD IRQFQLQHWL AI 512 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; IEA:InterPro.
 GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. 
Interpro
 IPR000175; Na/ntran_symport.
 IPR002435; Na/ntran_symport_noradrenaline. 
Pfam
 PF00209; SNF 
SMART
  
PROSITE
 PS00754; NA_NEUROTRAN_SYMP_2
 PS50267; NA_NEUROTRAN_SYMP_3 
PRINTS
 PR00176; NANEUSMPORT.
 PR01201; NORTRANSPORT.