CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028151
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mutagen-sensitive 301 
Protein Synonyms/Alias
 RE48845p 
Gene Name
 mus301 
Gene Synonyms/Alias
 CG7972; Dmel_CG7972 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
176KKPKTPEKLLAPLKDacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Helicase; Hydrolase; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1051 AA 
Protein Sequence
MANKHNLCKK RSLDLSEEST SESHAKRQCT ENLFWPEGED DDSFFSNAHL EDLLDGRKEE 60
LFGTQATTST NKMTQSGSDD GLGLFADTSF PSAQSVPPNS ASKPDEASAP TDKHQIDLAD 120
EENADKLFKK INLNDLSIAE MEDIFHGADD FSDPMVQNTQ LFLDAMTFKK PKTPEKLLAP 180
LKDDSMSFIS KSVIEGLVQG TQYVTCEELK NQSLLDPVNW ETQAFADFEK NNQDIDKFPS 240
KGEFYGLPDK VKKMILEHKG INSLYEWQDE CLNLPAIRQR KNLIYALPTS GGKTLVAEIL 300
MLRELLCRER NVLFILPYVS IVQEKVSAMS PFAIDLDFIV EEYTAGKGKC PPQPRRKRRS 360
LFIASIEKGA VLMDSLIDVQ RPHEIGLVVV DELHLIGEKG RGATLEAFLT KVMFLNANIQ 420
IVGMSATIGN LSEISSFLNA DVYTRGFRPV ELKEYIKCGP DLLEINSAGQ TLEEIFVPSR 480
SVEYNYSEAV KRADPDHLAG LISECAPEHC CLVFCPSRKN CENVALLLSR IVPKHKFFEH 540
RRSEKLDLMD ALDKMCGILS PVLAKTLPYG IAYHHSGLTT DERKYIETAY RFGVVTVICC 600
TSTLAAGVNL PAKRVIIRAP YVGQEFLTLC KYKQMVGRAG RAGLGEAGES ILIAQSKDNL 660
LVGQMLFSPM DKALSSLDQN EAVGLQSLIL SVVGLNLAEC RRDLNRLVNS TLLSVQAKSL 720
EVAVNEIVLR ILREMFKNKV LQLAEPQAKS KINSSDIITS QDVSQANRPA GDRRLLIGQS 780
TPFKLTNIGR AAFKAGIDYK RANAIHKELK QAQQQLILTN YLHLLYLVVC FNSNERGDEL 840
FPADASILFG VYTSLPLDSQ AMFKQLGFTE AHAARLFKTQ SVQGPLSLQL NRLYKVLILA 900
DILNLLPIPS VASKYNVERG TLQHLISQST AAASAIVRLC EELEEFWCYK PLFERILHKM 960
DRCGTFELEP LMELPAVKIN RARQLYAAGF QTIGDIARVR PSHLVQSLEH MPLRVATEIV 1020
SAAKIILMKK LDHLEEETEN LKDCLKTSDK N 1051 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
 GO:0004386; F:helicase activity; ISS:FlyBase.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC.
 GO:0016321; P:female meiosis chromosome segregation; IMP:FlyBase.
 GO:0007294; P:germarium-derived oocyte fate determination; IMP:FlyBase.
 GO:0008298; P:intracellular mRNA localization; IMP:FlyBase.
 GO:0030717; P:karyosome formation; IMP:FlyBase.
 GO:0009949; P:polarity specification of anterior/posterior axis; IMP:FlyBase.
 GO:0009951; P:polarity specification of dorsal/ventral axis; IMP:FlyBase.
 GO:0006417; P:regulation of translation; TAS:FlyBase. 
Interpro
 IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00270; DEAD
 PF00271; Helicase_C 
SMART
 SM00487; DEXDc
 SM00490; HELICc 
PROSITE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER 
PRINTS