CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000856
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dipeptidyl peptidase 3 
Protein Synonyms/Alias
 Dipeptidyl aminopeptidase III; Dipeptidyl arylamidase III; Dipeptidyl peptidase III; DPP III 
Gene Name
 Dpp3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
233LDSELTSKLKSYEFQacetylation[1]
609RVHLDRSKIRSVGKPacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Cleaves Arg-Arg-beta-naphthylamide. 
Sequence Annotation
 ACT_SITE 451 451
 METAL 450 450 Zinc; catalytic.
 METAL 455 455 Zinc; catalytic.  
Keyword
 Aminopeptidase; Complete proteome; Cytoplasm; Hydrolase; Metal-binding; Metalloprotease; Protease; Reference proteome; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 738 AA 
Protein Sequence
MADTQYILPN DIGVSSLDCR EAFRLLSPTE RLYAHHLSRA AWYGGLAVLL QTSPEAPYIY 60
ALLSRLFRAQ DPDQLRQHAL AEGLTEEEYQ AFLVYAAGVY SNMGNYKSFG DTKFVPNLPK 120
EKLERVILGS KAAQQHPEEV RSLWQTCGEL MFSLEPRLRH LGLGKEGVTT YFSGDCAMED 180
AKLAQDFLDS QNLSAYNTRL FKVVGQEGKY HYEVRLASVL NTEPALDSEL TSKLKSYEFQ 240
GNHFQVTRGD YAPILQKVVE HLEKAKAYAA NSHQEQMLAQ YVESFTQGSI EAHKRGSRFW 300
IQDKGPIVES YIGFIESYRD PFGSRGEFEG FVAMVNKDMS AKFERLVASA EQLLKELPWP 360
PAFEKDKFLT PDFTSLDVLT FAGSGIPAGI NIPNYDDLRQ TEGFKNVSLG NVLAVAYATK 420
REKLTFMEEE DKDLYIRWKG PSFDVQVGLH ELLGHGSGKL FVQDEKGAFN FDQETVINPE 480
TGEQIQSWYR SGETWDSKFS TIASSYEECR AESVGLYLCL NPQVLQIFGF EGTDAEDVIY 540
VNWLNMVRAG LLALEFYTPE TANWRQAHMQ ARFVILRVLL EAGEGLVTVT PTTGSDGRPD 600
ARVHLDRSKI RSVGKPALER FLRRLQVLKS TGDVVAGRAL YEGYAAVTDA PPECFLTLRD 660
TVLLRKESRK LIVQPNTRLE GSEVQLVEYE ASAAGLIRSF CERFPEDGPE LEEVLTQLAT 720
ADAQFWRDQV QEAPSGQA 738 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
 GO:0008239; F:dipeptidyl-peptidase activity; IEA:InterPro.
 GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IDA:RGD.
 GO:0006508; P:proteolysis; IDA:RGD. 
Interpro
 IPR005317; Dipeptidyl-peptase3. 
Pfam
  
SMART
  
PROSITE
  
PRINTS