Tag | Content |
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CPLM ID | CPLM-013617 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Vacuolar protein sorting-associated protein 13A |
Protein Synonyms/Alias | Chorea-acanthocytosis protein homolog; Chorein |
Gene Name | Vps13a |
Gene Synonyms/Alias | Chac; Kiaa0986 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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2221 | TNRMLQYKADGIHRK | ubiquitination | [1] | 2915 | GLAGAASKITSAMAK | ubiquitination | [1] | 2980 | KPIKGAQKEGAAGFF | ubiquitination | [1] | 3144 | FGKIVNFKTPEDARW | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May play a role in the control of protein cycling through the trans-Golgi network to early and late endosomes, lysosomes and plasma membrane (By similarity). |
Sequence Annotation | REPEAT 212 245 TPR 1. REPEAT 373 406 TPR 2. REPEAT 1806 1840 TPR 3. REPEAT 1999 2034 TPR 4. REPEAT 2716 2750 TPR 5. REPEAT 2852 2890 TPR 6. MOD_RES 2233 2233 Phosphotyrosine. MOD_RES 2234 2234 Phosphothreonine. |
Keyword | Alternative splicing; Complete proteome; Phosphoprotein; Protein transport; Reference proteome; Repeat; TPR repeat; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 3166 AA |
Protein Sequence | MVFESVVVEV LNRFLGDYVV NLDESQLSLG IWKGAVALKN LVIKENALHE LDVPFKVKVG 60 HIGSLKLKIP WKNLYTQPVE AVLEEIFLLI VPSSRIQYDP IKEEKQLMET KQQELKRIEK 120 AKQKVFDKEK PREEKQDTFT EKLVTQIIQN LQVQISSIHI RYEDDITNGD KPLSFGISLQ 180 NISLQTTDQY WIPCLHDNTE KLVRKLIRLD NLFAYWNVNS EMFYLNDYDE SLKALKNGIV 240 NENIVPEGYD FVFRPISASA KLQMNRRSDF DFSDPKINLA VDLHTIAIEF NKPQYFSLME 300 LLESIDMMTQ NQPYRKFKPS VPLHLHAKEW WAYAIHSILE VNVCPSLRMW SWEHIRNHRY 360 KMKRYREFYK KKLTSKKPSP EILMSLEELE KTLDVFNITI ARQQAEVEAK KAGYKIYKEG 420 VKDPEDNAGW FGWLWTWSES NANQQQDVKP GILEEMLTPE EKSLLYEAIG YSETAVDPTL 480 PKTFEALKFF VHLKSMSIVL RENHQKPELL NVVVEGLSTS VVQRPGAQAI KFETKIDSFH 540 ITGLPDDFKK PHLLSSLDDT SLLQITFEIN PLNETVAQRC TIEAEPLEII YDARTVNSIV 600 EFFRPPKDVH LAQLTSVTLT KLEEFRAKTA TGLLYVIETQ KVLDLRINVK ASYVIVPQYG 660 NFSPTSNLLL LDLGHLKVSS KRRSLLPDVR PSEASLEDIM HRAYDSFDIQ LTSIQLLYSR 720 VGDNWKEARK LNVSTQHILI PMHVNVELSK AMVFMDIKMP KFKISGKLPL VSLRISDKKL 780 QGIMELLGSI PKPEPVTDVS APARSFQIQA SALPVSHISQ KLIPLLEQPV TEDDSEEEFF 840 DAPCSPLEEC PQVSCRDKCT RQKKLQKKDC VMNLIQLRMR FEVAEVSIQF YHLVGDCELP 900 VLEMGALGLG TEAEFRTFDL KGSAFLKELW LKCPEYLDEN KKPVYLITTL DNTMEDLLTL 960 EFMKVEKNAP NLNSTYNNVL QLIKVNFSSL DIHLHTEALL NTMNYLNNIL PELREKSASV 1020 SAAEPEDKGD IIKKLALKLP TNEDIITLQL LAELSCLQIF IQDQKQNISE IKIEGLDSEM 1080 IMKPLVTEIN AKLRNIIVLD SDKMAIYKKA LYITGKEVFS FKMISYMDAT AGYAYTDMSV 1140 VDIRVHLTVG CIEVVFITKF LYSILAFIDN FQAVKDALAE ATVQAAEMAA DGVKELARKS 1200 SRFALDVNIK APVVLIPQSP VSQNVFVADF GLITMKNIFV TVTETQSNIP PVIDLITIKL 1260 SKMRLYRSQF RNDTYQEVLD LLLPLNLEVI VERNLSWEWY KEVPCFNIKA QLKPMEFILS 1320 QEDLTTVFQT LHGNIWYGQD LSAPSSANKD PETMTSGVTS PPDHSPATVV TAAVVEVHPQ 1380 ASQAHTMLNV SFQTDYLTMA LYSPGPDEAS FTDVRDPSLE LAEFKLENII SSLKIYTDDS 1440 TVFSFSVKNC ILDDKRSHVM KATPRMIGLT VGFDKKDMVD IKYRKIKTFV VTDAVVQEMY 1500 VCASVEFLMT VAHIFFDAYM TSTALETSVQ TRTTREAPAQ ELGKWEMNIL IKNPEIVFVA 1560 DMTRNDAPAL VITTQCEICC KGEPTSNTVT AAIKDLQVRA CPFLPVKRKG KVTTVLQPCD 1620 LFYQATQLGR DPQMIDISVK SLTLKVSPVI INTIITITSA LYTTKETVPE ENTSNIAHLW 1680 DKKDTKNLKM WFLEESNESE KVVPTNEVMP GGETLNLRID SIFIVLEAGI GHRTVPMLLA 1740 KACFSGESKN WLSLINLHCH LELEVHYYNE MFGVWEPLLE PLEIDQTDDF RPWNLGIKMK 1800 KKAKEAIVES DSEAENYKVP EYKTAISFYS RDQLNITLSK CGLVMLNNLV EAFTEAATGS 1860 SSVFLRDLAP FMIFNSLGLT VSVSPSDSFS VLNVPLAKSY ELKNDESLSM DYVRTKDNDH 1920 FNAMTSLSSK LFFILLTPAN HSVADKIPLT KVGRRLYTVR HRESGVERSI ICQIDTVEGS 1980 KKVTIRSPVQ IKNHFSIPIS VFEGDTLLGI ASPENEFNIP LASYRSSLSL VPEDQDYQLC 2040 EGIDFEEIIK YDGQLLKKKC RSTNPSKKSF VINIVPEKDN LASLSVYSED GWDLPYVLHL 2100 WPPILIRNLL PYKVAYYIEG IENTVVTLSE GHSSQIYNVE MDQAKLHLKL LDYLNHDWKS 2160 EFYIRSSQQD INFINFTCLT EMEKSDLDIA IHMTYNTGQT VVAFHSPYWM VNKTNRMLQY 2220 KADGIHRKHP PNYTKPVLFS FQPNHFFNNN KVQLMVTDSE LSDQFSIDTV GSHGAIRCKG 2280 LKMEYQVGVT INLSSFNITR IVTFIPFYMI KNKSKYHISV AEEGSDKWLS LDLEQSIPFW 2340 PENASNILLI QVERSEDPPK RIYFNKQDNC ILLRLNNELG GIIAEVNLAE HSTVITFSDY 2400 HDGAATFLLI NHTKSDPVQY NQSSLGEIED SLPPGKAVYY TWADPVGSRK LKWSCGQSYG 2460 EVTHKDDMMT PISVGKKTIY LVSFFEGLQR IILFTEDPRV FKVTYESEKA ELAELEVVLA 2520 LQDVGISLVN NYTKQEVAYI GITSSDVVWE AKPKKKARWK PMSVKHTEKL EKEFREYTEA 2580 SPLEDKVVEL DNIPVRLTPS GNDMKILQPH VIPVRRNYLP ALKVEYNTSA HQSSFRIQIY 2640 RIQIQNQIHG AIFPFVFYPI KPPRSVTMDS APKPFTDVSI VMRSAGHSQI SRIKYFKVLI 2700 QEMDLSLDLG FVYALADLVT KAEVTEKTEV EHFHKDVEAF EQEYEVVSSV DQSQVNLFEY 2760 FHISPIKLHL SVSLSSGRDE AKDSEQHGGL IPVHSLNLLL KSIGATLTDV QDVVFKLAFF 2820 ELNYQFHTTS ELQSEVIRHY SKQAIKQMYV LILGLDVLGN PFGLIREFSE GVEAFFYEPY 2880 QGAIQGPEEF VEGMALGLKA LVGGAVGGLA GAASKITSAM AKGVAAMTMD EDYQQKRREA 2940 MNKQPAGLRE GITRGGKGLV SGFVSGITGI VTKPIKGAQK EGAAGFFKGV GKGLVGAVTR 3000 PTGGIIDMAS STFQGIKRAT ETSEVESLRP PRFFNEDGVI RPYRLRDGSG NQMLQVMENG 3060 RFAKYKYFTH VMINKTDMFM ITRRGVLFVT KGTFGQLTCE WQYTFDEFTK EPFIVHGRRL 3120 RIEAKERVKS VFHAKEFGKI VNFKTPEDAR WILTKLEEAR EPSPRL 3166 |
Gene Ontology | |
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Pfam | |
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