CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015819
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 503 
Protein Synonyms/Alias
 Zinc finger protein Nolz-1 
Gene Name
 Znf503 
Gene Synonyms/Alias
 Nolz1; Zfp503 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
213GGGVAAEKSGFRVPSacetylation[1, 2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
 May function as a transcriptional repressor (By similarity). 
Sequence Annotation
 ZN_FING 520 548 C2H2-type.  
Keyword
 Alternative splicing; Complete proteome; Metal-binding; Nucleus; Reference proteome; Repressor; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 652 AA 
Protein Sequence
MSTAPSLSAL RSSKHSGGGG GGGGGGGSGG GSADPAWTSA LSGNCSGHGP GSSPAGSTKP 60
FVHAVPPSDP LRQANRLPIK VLKMLTARTG HILHPEYLQP LPSTPVSPIE LDAKKSPLAL 120
LAQTCSQIGK PDPSPSSKLS SVASNGGGAG GAGNGAGGDK DAKSGPLKLS DIGVEDKSSF 180
KPYSKPGSDK KEPGGGGGGG GGGGGGGGVA AEKSGFRVPS ATCQPFTPRT GSPSSSASAC 240
SPGGMLPSAG GGPEGKDDKK DPEAGGGGSS KGSGGASADG VPAGLGHGRI SCGGGINVDV 300
NQHSEGGPGG KALGSDCGGS SSSSSGSGPS APTSSSVLGS GLVAPVSPYK PGQTVFPLPP 360
AGMTYPGSLA GAYAGYPPQF LPHGVALDPT KPGSLVGAQL AAAAAGSLGC SKPAGSSPLA 420
GASPPSVMTA SLCRDPYCLS YHCASHLAGA AAASASCAHD PAAAAAALKS GYPLVYPTHP 480
LHGVHSSLTA AAAAGATPPS LAGHPLYPYG FMLPNDPLPH ICNWVSANGP CDKRFATSEE 540
LLSHLRTHTA FPGTDKLLSG YPSSSSLASA AAAAMACHMH IPTSGAPGSP GTLALRSPHH 600
ALGLSSRYHP YSKSPLPTPG APVPVPAATG PYYSPYALYG QRLTTASALG YQ 652 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR022129; Tscrpt_rep_NocA-like.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF12402; nlz1 
SMART
 SM00355; ZnF_C2H2 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS