CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003060
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein TolB 
Protein Synonyms/Alias
  
Gene Name
 tolB 
Gene Synonyms/Alias
 b0740; JW5100 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
67ADLRNSGKFNPLDRAacetylation[1]
155ASDEVFEKLTGIKGAacetylation[1]
213AWSPDGSKLAYVTFEacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Involved in the TonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K). Necessary for the colicins to reach their respective targets after initial binding to the bacteria. 
Sequence Annotation
  
Keyword
 3D-structure; Bacteriocin transport; Complete proteome; Direct protein sequencing; Periplasm; Protein transport; Reference proteome; Signal; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 430 AA 
Protein Sequence
MKQALRVAFG FLILWASVLH AEVRIVIDSG VDSGRPIGVV PFQWAGPGAA PEDIGGIVAA 60
DLRNSGKFNP LDRARLPQQP GSAQEVQPAA WSALGIDAVV VGQVTPNPDG SYNVAYQLVD 120
TGGAPGTVLA QNSYKVNKQW LRYAGHTASD EVFEKLTGIK GAFRTRIAYV VQTNGGQFPY 180
ELRVSDYDGY NQFVVHRSPQ PLMSPAWSPD GSKLAYVTFE SGRSALVIQT LANGAVRQVA 240
SFPRHNGAPA FSPDGSKLAF ALSKTGSLNL YVMDLASGQI RQVTDGRSNN TEPTWFPDSQ 300
NLAFTSDQAG RPQVYKVNIN GGAPQRITWE GSQNQDADVS SDGKFMVMVS SNGGQQHIAK 360
QDLATGGVQV LSSTFLDETP SLAPNGTMVI YSSSQGMGSV LNLVSTDGRF KARLPATDGQ 420
VKFPAWSPYL 430 
Gene Ontology
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0030288; C:outer membrane-bounded periplasmic space; IDA:EcoliWiki.
 GO:0043213; P:bacteriocin transport; IMP:EcoliWiki.
 GO:0017038; P:protein import; IMP:EcoliWiki.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR011659; PD40.
 IPR002469; Peptidase_S9B.
 IPR014167; Tol-Pal_propeller_TolB.
 IPR007195; TolB_N.
 IPR015943; WD40/YVTN_repeat-like_dom. 
Pfam
 PF00930; DPPIV_N
 PF07676; PD40
 PF04052; TolB_N 
SMART
  
PROSITE
  
PRINTS