CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041293
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Loss of heterozygosity 12 chromosomal region 1 protein 
Protein Synonyms/Alias
 Loss of heterozygosity, 12, chromosomal region 1, isoform CRA_c 
Gene Name
 LOH12CR1 
Gene Synonyms/Alias
 hCG_27699 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
11SPAKHRAKMDDIVVVubiquitination[1]
48PTFQPLLKGLLSGQTubiquitination[2]
61QTSPTNAKLEKLDSQubiquitination[1, 2, 3]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 177 AA 
Protein Sequence
MTPSPAKHRA KMDDIVVVAQ GSQASRNVSN DPDVIKLQEI PTFQPLLKGL LSGQTSPTNA 60
KLEKLDSQQV LQLCLRYQDH LHQCAEAVAF DQNALVKRIK EMDLSVETLF SFMQERQKRY 120
AKYAEQIQKV NEMSAILRRI QMGIDQTVPL LDRLNSMLPE GERLEPFSMK PDRELRL 177 
Gene Ontology
  
Interpro
 IPR018780; Tumour_suppressor_LOH1CR12. 
Pfam
 PF10158; LOH1CR12 
SMART
  
PROSITE
  
PRINTS